Structure of Soluble Dietary Fiber from Fresh Rice at the Medium-Milk Stage and Improvement of Insulin Resistance in HepG2 Cells
Fresh rice (Oryza sativa ssp. japonica) at the medium-milk stage is rich in soluble dietary fiber (SDF), leading to potential effects on type 2 diabetes (T2D). In this study, we analyzed each monosaccharide, the relative molecular weight, and the molecular linkages of fresh rice (grain, stem, husk,...
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| Format: | Article |
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Wiley
2022-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2022/8714216 |
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| author | Aiwu Zhang Ren Li Qi Wang Guoliang Zhao Linyan Zhang Peng Jiang Nian Liu Zhijiang Li |
| author_facet | Aiwu Zhang Ren Li Qi Wang Guoliang Zhao Linyan Zhang Peng Jiang Nian Liu Zhijiang Li |
| author_sort | Aiwu Zhang |
| collection | DOAJ |
| description | Fresh rice (Oryza sativa ssp. japonica) at the medium-milk stage is rich in soluble dietary fiber (SDF), leading to potential effects on type 2 diabetes (T2D). In this study, we analyzed each monosaccharide, the relative molecular weight, and the molecular linkages of fresh rice (grain, stem, husk, and leaf) SDF. The examined fresh rice leaf SDF consisted of 31.9% glucose, 35.7% galactose, 15.3% arabinose, 11.7% mannose, and a small amount of rhamnose and xylose. The molecular weight (Mw) was 232.5±19.1×104 u, and the radius of gyration (Rg) was 298.8±25.4 nm. The glycosidic bonds consisted mainly of Araf and Glc/Gal and included 1,3-Araf, 1,5-Araf, and 3,5-Araf glycosidic bonds. The effect of fresh rice leaf SDF on insulin resistance (IR) in HepG2 cells showed that it could significantly enhance glucose consumption (P<0.05). It also decreased the malondialdehyde (MDA) content (P<0.05) and increased the total superoxide dismutase (T-SOD) and glutathione peroxidase (GSH-Px) activities (P<0.05) in a dose-dependent manner. Therefore, fresh rice leaf SDF might be a good dietary supplement for treating T2D. |
| format | Article |
| id | doaj-art-eef852d2c6c94b1aad66e34e2fbae46f |
| institution | DOAJ |
| issn | 2090-9071 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
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| series | Journal of Chemistry |
| spelling | doaj-art-eef852d2c6c94b1aad66e34e2fbae46f2025-08-20T03:21:15ZengWileyJournal of Chemistry2090-90712022-01-01202210.1155/2022/8714216Structure of Soluble Dietary Fiber from Fresh Rice at the Medium-Milk Stage and Improvement of Insulin Resistance in HepG2 CellsAiwu Zhang0Ren Li1Qi Wang2Guoliang Zhao3Linyan Zhang4Peng Jiang5Nian Liu6Zhijiang Li7College of Food ScienceCollege of Food ScienceCollege of Food ScienceCollege of Food ScienceCollege of Humanities and Social SciencesCollege of Food ScienceCollege of Food ScienceCollege of Food ScienceFresh rice (Oryza sativa ssp. japonica) at the medium-milk stage is rich in soluble dietary fiber (SDF), leading to potential effects on type 2 diabetes (T2D). In this study, we analyzed each monosaccharide, the relative molecular weight, and the molecular linkages of fresh rice (grain, stem, husk, and leaf) SDF. The examined fresh rice leaf SDF consisted of 31.9% glucose, 35.7% galactose, 15.3% arabinose, 11.7% mannose, and a small amount of rhamnose and xylose. The molecular weight (Mw) was 232.5±19.1×104 u, and the radius of gyration (Rg) was 298.8±25.4 nm. The glycosidic bonds consisted mainly of Araf and Glc/Gal and included 1,3-Araf, 1,5-Araf, and 3,5-Araf glycosidic bonds. The effect of fresh rice leaf SDF on insulin resistance (IR) in HepG2 cells showed that it could significantly enhance glucose consumption (P<0.05). It also decreased the malondialdehyde (MDA) content (P<0.05) and increased the total superoxide dismutase (T-SOD) and glutathione peroxidase (GSH-Px) activities (P<0.05) in a dose-dependent manner. Therefore, fresh rice leaf SDF might be a good dietary supplement for treating T2D.http://dx.doi.org/10.1155/2022/8714216 |
| spellingShingle | Aiwu Zhang Ren Li Qi Wang Guoliang Zhao Linyan Zhang Peng Jiang Nian Liu Zhijiang Li Structure of Soluble Dietary Fiber from Fresh Rice at the Medium-Milk Stage and Improvement of Insulin Resistance in HepG2 Cells Journal of Chemistry |
| title | Structure of Soluble Dietary Fiber from Fresh Rice at the Medium-Milk Stage and Improvement of Insulin Resistance in HepG2 Cells |
| title_full | Structure of Soluble Dietary Fiber from Fresh Rice at the Medium-Milk Stage and Improvement of Insulin Resistance in HepG2 Cells |
| title_fullStr | Structure of Soluble Dietary Fiber from Fresh Rice at the Medium-Milk Stage and Improvement of Insulin Resistance in HepG2 Cells |
| title_full_unstemmed | Structure of Soluble Dietary Fiber from Fresh Rice at the Medium-Milk Stage and Improvement of Insulin Resistance in HepG2 Cells |
| title_short | Structure of Soluble Dietary Fiber from Fresh Rice at the Medium-Milk Stage and Improvement of Insulin Resistance in HepG2 Cells |
| title_sort | structure of soluble dietary fiber from fresh rice at the medium milk stage and improvement of insulin resistance in hepg2 cells |
| url | http://dx.doi.org/10.1155/2022/8714216 |
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