Influence of respiratory disease experiences on COVID-19 vaccine acceptance: a study from Southeastern Louisiana

IntroductionRespiratory diseases, including influenza (flu) and respiratory syncytial virus, continue to be major health concerns globally. The onset of COVID-19 further compounded these issues, making it important to examine public attitudes toward vaccination and understanding of respiratory disea...

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Main Authors: Saba Barri, Sara Al-Dahir, Klaus Heyer, Ashley Taylor, Alaa Khalil, Mohamed Belkhouche, Brooke-Ashleigh Bonvillain, Kathryn Caldwell, Heather Surcouf, Ibrahim Hamed, Malack Jwayyed, Leslie S. Craig, Daniel F. Sarpong, Daniel Salmon
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1593861/full
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Summary:IntroductionRespiratory diseases, including influenza (flu) and respiratory syncytial virus, continue to be major health concerns globally. The onset of COVID-19 further compounded these issues, making it important to examine public attitudes toward vaccination and understanding of respiratory diseases. This study explores factors influencing decisions to receive the latest COVID-19 vaccine, focusing specifically on the role of prior respiratory illness diagnosis.MethodsA follow-up survey among 299 participants from Southeastern Louisiana across 10 healthcare facilities was administered via phone and the Qualtrics platform, gathering information about the likelihood of receiving the latest COVID-19 vaccine. Quantitative data were analyzed using log-binomial and Poisson regression models to assess relationships between respiratory illness history and COVID-19 vaccine acceptance.ResultsNearly half (47%) of the participants reported a history of respiratory illness. Individuals with prior respiratory diagnosis were more likely to accept the latest COVID-19 vaccine (62%) than those without (41%) (RR: 1.79, 95% CI: 1.26–2.56). In fully adjusted models, accounting for age, prior vaccine hesitancy, and comorbidities, influenza vaccine acceptance (RR: 1.87, 95% CI: 1.06–3.28) was associated with greater likelihood of receiving the latest COVID-19 vaccine. Key barriers to vaccination, including concerns about side effects and distrust in vaccine efficacy were identified.DiscussionParticipants with respiratory illnesses and those with positive vaccination histories, particularly regarding influenza, showed a higher likelihood of accepting the latest COVID-19 vaccines. However, significant obstacles to vaccine uptake persist. Tailored public health efforts that address these concerns are crucial to improving vaccine rates, particularly among hesitant groups.
ISSN:2296-2565