Potentially causal associations between placental DNA methylation and schizophrenia and other neuropsychiatric disorders

Potentially causal associations between placental DNA methylation and schizophrenia and other neuropsychiatric disorders

Abstract Increasing evidence supports the role of the placenta in neurodevelopment and in the onset of neuropsychiatric disorders. Recently, mQTL and iQTL maps have proven useful in understanding relationships between SNPs and GWAS that are not captured by eQTL. In this context, we propose that part...

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Main Authors: Ariadna Cilleros-Portet, Corina Lesseur, Sergi Marí, Marta Cosin-Tomas, Manuel Lozano, Amaia Irizar, Amber Burt, Iraia García-Santisteban, Diego Garrido-Martín, Geòrgia Escaramís, Alba Hernangomez-Laderas, Raquel Soler-Blasco, Charles E. Breeze, Bárbara P. Gonzalez-Garcia, Loreto Santa-Marina, Jia Chen, Sabrina Llop, Mariana F. Fernández, Martine Vrijheid, Jesús Ibarluzea, Mònica Guxens, Carmen Marsit, Mariona Bustamante, Jose Ramon Bilbao, Nora Fernandez-Jimenez
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57760-3
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