Liquid Chromatography-Tandem Mass Spectrometry Method Development and Validation for the Determination of a New Mitochondrial Antioxidant in Mouse Liver and Cerebellum, Employing Advanced Chemometrics

Liquid Chromatography-Tandem Mass Spectrometry Method Development and Validation for the Determination of a New Mitochondrial Antioxidant in Mouse Liver and Cerebellum, Employing Advanced Chemometrics

Anxiety and stress-related disorders affect all ages in all geographical areas. As high anxiety and chronic stress result in the modulation of mitochondrial pathways, intensive research is being carried out on pharmaceutical interventions that alleviate pertinent symptomatology. Therefore, innovativ...

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Bibliographic Details
Main Authors: Anthi Panara, Dimitra Biliraki, Markus Nussbaumer, Michaela D. Filiou, Nikolaos S. Thomaidis, Ioannis K. Kostakis, Evagelos Gikas
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Molecules
Subjects:
triphenylphospine-hydroxytyrosol (TPP-HT)
mitochondria
LC-MS/MS
cerebellum
liver
chemometrics
Online Access:https://www.mdpi.com/1420-3049/30/9/1900
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