Deep learning for the detection of microsatellite instability from histology images in colorectal cancer: A systematic literature review

Deep learning for the detection of microsatellite instability from histology images in colorectal cancer: A systematic literature review

Microsatellite instability (MSI) or deficient mismatch repair (dMMR) is a clinically important genetic feature affecting 10–15% of colorectal cancer (CRC) patients. Patients with metastatic MSI/dMMR CRC are eligible for therapy with immune checkpoint inhibitors, making MSI/dMMR the most important im...

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Main Authors: Amelie Echle, Narmin Ghaffari Laleh, Peter L. Schrammen, Nicholas P. West, Christian Trautwein, Titus J. Brinker, Stephen B. Gruber, Roman D. Buelow, Peter Boor, Heike I. Grabsch, Philip Quirke, Jakob N. Kather
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:ImmunoInformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S2667119021000082
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