Three-dimensional genome structures of single mammalian sperm

Abstract The three-dimensional (3D) organization of chromosomes is crucial for packaging a large mammalian genome into a confined nucleus and ensuring proper nuclear functions in somatic cells. However, the packaging of the much more condensed sperm genome is challenging to study with traditional im...

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Bibliographic Details
Main Authors: Heming Xu, Yi Chi, Changjian Yin, Cheng Li, Yujie Chen, Zhiyuan Liu, Xiaowen Liu, Hao Xie, Zi-Jiang Chen, Han Zhao, Keliang Wu, Shigang Zhao, Dong Xing
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59055-z
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