纳米材料在缺血性卒中诊疗中的研究进展及挑战 Research Progress and Challenges of Nanomaterials in the Diagnosis and Treatment of Ischemic Stroke

纳米材料在缺血性卒中诊疗中的研究进展及挑战 Research Progress and Challenges of Nanomaterials in the Diagnosis and Treatment of Ischemic Stroke

卒中是中国居民致死和长期致残的主要原因，传统的治疗药物受限于血脑屏障阻碍、稳定性差、缺乏靶向性、低载药量，治疗效果可能欠理想。纳米材料作为一种新兴的、非侵入性、可实时控制的药物，已被广泛用于卒中的诊疗。纳米药物能够有效提高药物的生物相容性、稳定性、靶向性，并延长药物的半衰期，从而有效改善传统药物的疗效。近年来纳米材料在缺血性卒中诊疗领域取得了一定进展，但仍面临临床转化等挑战。本文主要综述纳米材料在缺血性卒中诊疗中的研究进展和挑战，旨在继续推动纳米材料在卒中诊疗中的研究与应用。 Abstract: Stroke is a major cause of death and long-term...

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Bibliographic Details
Main Author: 张丽苹1*，曹黎明2*，肖楠1，3，廖雨琦1，池枫1，余艳妮1，3，任力杰1（*第一作者） (ZHANG Liping1*, CAO Liming2*, XIAO Nan1,3, LIAO Yuqi1, CHI Feng1, YU Yanni1,3, REN Lijie1 (*contributed equally). )
Format: Article
Language:zho
Published: Editorial Department of Chinese Journal of Stroke 2024-09-01
Series:Zhongguo cuzhong zazhi
Subjects:
缺血性卒中
纳米材料
血脑屏障
靶向治疗
诊疗
挑战
ischemic stroke
nanomaterial
blood-brain barrier
targeted therapy
diagnosis and treatment
challenge
Online Access:http://www.chinastroke.org.cn/CN/article/openArticlePDF.jsp?id=4108
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