Non-Target Metabolomics Reveals Changes in Metabolite Profiles in Distant Hybrid Incompatibility Between <i>Paeonia</i> sect. <i>Moutan </i>and<i> P. lactiflora</i>

Peonies are globally renowned ornamental plants, and distant hybridization is a key method for breeding new varieties, though it often faces cross-incompatibility challenges. The metabolic mechanisms underlying the crossing barrier between tree peony (<i>Paeonia</i> sect<i>. Moutan...

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Main Authors: Wenqing Jia, Yingyue Yu, Zhaorong Mi, Yan Zhang, Guodong Zhao, Yingzi Guo, Zheng Wang, Erqiang Wang, Songlin He
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Plants
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Online Access:https://www.mdpi.com/2223-7747/14/9/1381
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Summary:Peonies are globally renowned ornamental plants, and distant hybridization is a key method for breeding new varieties, though it often faces cross-incompatibility challenges. The metabolic mechanisms underlying the crossing barrier between tree peony (<i>Paeonia</i> sect<i>. Moutan</i>) and herbaceous peony (<i>P. lactiflora</i>) remain unclear. To identify key metabolites involved in cross-incompatibility, we performed a cross between <i>P. ostii</i> ‘Fengdanbai’ (female parent) and <i>P. lactiflora</i> ‘Red Sara’ (male parent) and analyzed metabolites in the stigma 12 h after pollination using UPLC-MS. We identified 1242 differential metabolites, with 433 up-regulated and 809 down-regulated, including sugars, nucleotides, amino acids, lipids, organic acids, benzenoids, flavonoids, and alkaloids. Most differential metabolites were down-regulated in hybrid stigmas, potentially affecting pollen germination and pollen tube growth. Cross-pollinated stigma exhibited lower levels of high-energy nutrients (such as amino acids, nucleotides, and tricarboxylic acid cycle metabolites) compared to self-pollinated stigma, which suggests that energy deficiency is a contributing factor to the crossing barrier. Additionally, cross-pollination significantly impacted KEGG pathways such as nucleotide metabolism, purine metabolism, and vitamin B6 metabolism, with most metabolites in these pathways being down-regulated. These findings provide new insights into the metabolic basis of cross-incompatibility between tree and herbaceous peonies, offering a foundation for overcoming hybridization barriers in peony breeding.
ISSN:2223-7747