Treatment of Neuropathic Pain: Focus on Antidepressants, Opioids and Gabapentin

BACKGROUND: The treatment of neuropathic pain continues to be difficult. Randomized, controlled trials (RCTs) provide some evidence to guide therapy. Most data relate to antidepressant therapy, although there is information on anticonvulsants and other treatments. Mistaken beliefs about many of thes...

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Main Authors: C Peter N Watson, Judith H Watt-Watson
Format: Article
Language:English
Published: Wiley 1999-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/1999/961273
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author C Peter N Watson
Judith H Watt-Watson
author_facet C Peter N Watson
Judith H Watt-Watson
author_sort C Peter N Watson
collection DOAJ
description BACKGROUND: The treatment of neuropathic pain continues to be difficult. Randomized, controlled trials (RCTs) provide some evidence to guide therapy. Most data relate to antidepressant therapy, although there is information on anticonvulsants and other treatments. Mistaken beliefs about many of these treatments are prevalent and need to be dispelled. Opioids are increasingly being used for the refractory patient. There has been recent enthusiasm for the anticonvulsant gabapentin for the treatment of these conditions.
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spelling doaj-art-ee618a32152644749429af7ff09688362025-02-03T01:02:29ZengWileyPain Research and Management1203-67651999-01-014416817810.1155/1999/961273Treatment of Neuropathic Pain: Focus on Antidepressants, Opioids and GabapentinC Peter N Watson0Judith H Watt-Watson1Department of Medicine, University of Toronto, Toronto, Ontario, CanadaFaculty of Nursing, University of Toronto, Toronto, Ontario, CanadaBACKGROUND: The treatment of neuropathic pain continues to be difficult. Randomized, controlled trials (RCTs) provide some evidence to guide therapy. Most data relate to antidepressant therapy, although there is information on anticonvulsants and other treatments. Mistaken beliefs about many of these treatments are prevalent and need to be dispelled. Opioids are increasingly being used for the refractory patient. There has been recent enthusiasm for the anticonvulsant gabapentin for the treatment of these conditions.http://dx.doi.org/10.1155/1999/961273
spellingShingle C Peter N Watson
Judith H Watt-Watson
Treatment of Neuropathic Pain: Focus on Antidepressants, Opioids and Gabapentin
Pain Research and Management
title Treatment of Neuropathic Pain: Focus on Antidepressants, Opioids and Gabapentin
title_full Treatment of Neuropathic Pain: Focus on Antidepressants, Opioids and Gabapentin
title_fullStr Treatment of Neuropathic Pain: Focus on Antidepressants, Opioids and Gabapentin
title_full_unstemmed Treatment of Neuropathic Pain: Focus on Antidepressants, Opioids and Gabapentin
title_short Treatment of Neuropathic Pain: Focus on Antidepressants, Opioids and Gabapentin
title_sort treatment of neuropathic pain focus on antidepressants opioids and gabapentin
url http://dx.doi.org/10.1155/1999/961273
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