Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety
Seventeen novel N-phenylbenzamide derivatives bearing a trifluoromethylpyrimidine moiety were synthesized via four-step reactions. Their antifungal and insecticidal properties were evaluated. Antifungal test results demonstrated that some of the synthesized compounds showed better in vitro bioactivi...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2021/8370407 |
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| author | Xuetong Yu Wenjun Lan Meihang Chen Su Xu Xiaoxi Luo Shuhong He Haijiang Chen Qiang Fei Wenneng Wu |
| author_facet | Xuetong Yu Wenjun Lan Meihang Chen Su Xu Xiaoxi Luo Shuhong He Haijiang Chen Qiang Fei Wenneng Wu |
| author_sort | Xuetong Yu |
| collection | DOAJ |
| description | Seventeen novel N-phenylbenzamide derivatives bearing a trifluoromethylpyrimidine moiety were synthesized via four-step reactions. Their antifungal and insecticidal properties were evaluated. Antifungal test results demonstrated that some of the synthesized compounds showed better in vitro bioactivities against Phomopsis sp., Botryosphaeria dothidea (B. dothidea), and Botrytis cinerea (B. cinerea) at 50 μg/mL than pyrimethanil. Unfortunately, the synthesized compounds revealed lower insecticidal activities against Spodoptera frugiperda (S. frugiperda) and Mythimna separata (M. separata) at 500 μg/mL than chlorantraniliprole. |
| format | Article |
| id | doaj-art-ee5abe973de54ab2887e3cbcd47a194c |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-ee5abe973de54ab2887e3cbcd47a194c2025-02-03T01:24:44ZengWileyJournal of Chemistry2090-90632090-90712021-01-01202110.1155/2021/83704078370407Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine MoietyXuetong Yu0Wenjun Lan1Meihang Chen2Su Xu3Xiaoxi Luo4Shuhong He5Haijiang Chen6Qiang Fei7Wenneng Wu8Food and Pharmaceutical Engineering Institute, Guiyang University, Guiyang 550003, ChinaFood and Pharmaceutical Engineering Institute, Guiyang University, Guiyang 550003, ChinaMaterial and Chemistry Engineering Institute, Tongren College, Tongren 554300, ChinaFood and Pharmaceutical Engineering Institute, Guiyang University, Guiyang 550003, ChinaFood and Pharmaceutical Engineering Institute, Guiyang University, Guiyang 550003, ChinaFood and Pharmaceutical Engineering Institute, Guiyang University, Guiyang 550003, ChinaFood and Pharmaceutical Engineering Institute, Guiyang University, Guiyang 550003, ChinaFood and Pharmaceutical Engineering Institute, Guiyang University, Guiyang 550003, ChinaFood and Pharmaceutical Engineering Institute, Guiyang University, Guiyang 550003, ChinaSeventeen novel N-phenylbenzamide derivatives bearing a trifluoromethylpyrimidine moiety were synthesized via four-step reactions. Their antifungal and insecticidal properties were evaluated. Antifungal test results demonstrated that some of the synthesized compounds showed better in vitro bioactivities against Phomopsis sp., Botryosphaeria dothidea (B. dothidea), and Botrytis cinerea (B. cinerea) at 50 μg/mL than pyrimethanil. Unfortunately, the synthesized compounds revealed lower insecticidal activities against Spodoptera frugiperda (S. frugiperda) and Mythimna separata (M. separata) at 500 μg/mL than chlorantraniliprole.http://dx.doi.org/10.1155/2021/8370407 |
| spellingShingle | Xuetong Yu Wenjun Lan Meihang Chen Su Xu Xiaoxi Luo Shuhong He Haijiang Chen Qiang Fei Wenneng Wu Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety Journal of Chemistry |
| title | Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety |
| title_full | Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety |
| title_fullStr | Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety |
| title_full_unstemmed | Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety |
| title_short | Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety |
| title_sort | synthesis and antifungal and insecticidal activities of novel n phenylbenzamide derivatives bearing a trifluoromethylpyrimidine moiety |
| url | http://dx.doi.org/10.1155/2021/8370407 |
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