Immune Escape Mechanisms in Colorectal Cancer Pathogenesis and Liver Metastasis

Immune Escape Mechanisms in Colorectal Cancer Pathogenesis and Liver Metastasis

Over the past decade, growing evidence indicates that the tumor microenvironment (TME) contributes with genomic/epigenomic aberrations of malignant cells to enhance cancer cells survival, invasion, and dissemination. Many factors, produced or de novo synthesized by immune, stromal, or malignant cell...

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Main Authors: Massimo Pancione, Guido Giordano, Andrea Remo, Antonio Febbraro, Lina Sabatino, Erminia Manfrin, Michele Ceccarelli, Vittorio Colantuoni
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2014/686879
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