Dexamethasone Suppressed LPS-Induced Matrix Metalloproteinase and Its Effect on Endothelial Glycocalyx Shedding

Dexamethasone Suppressed LPS-Induced Matrix Metalloproteinase and Its Effect on Endothelial Glycocalyx Shedding

The aim of this study is to determine the mechanism of sepsis-induced vascular hyperpermeability and the beneficial effect of glucocorticoid in protecting vascular endothelium. Male Sprague-Dawley rats were given either a bolus intraperitoneal injection of a nonlethal dose of LPS (Escherichia coli 0...

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Bibliographic Details
Main Authors:	Na Cui, Hao Wang, Yun Long, Longxiang Su, Dawei Liu
Format:	Article
Language:	English
Published:	Wiley 2015-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2015/912726
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