New Strategies and In Vivo Monitoring Methods for Stem Cell-Based Anticancer Therapies

Cancer is a devastating disease and the second cause of death in the developed world. Despite significant advances in recent years, such as the introduction of targeted therapies such as receptor tyrosine kinase inhibitors and immunotherapy, current approaches are insufficient to stop the advance of...

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Main Authors: Ping Wang, Aitor Aguirre
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2018/7315218
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author Ping Wang
Aitor Aguirre
author_facet Ping Wang
Aitor Aguirre
author_sort Ping Wang
collection DOAJ
description Cancer is a devastating disease and the second cause of death in the developed world. Despite significant advances in recent years, such as the introduction of targeted therapies such as receptor tyrosine kinase inhibitors and immunotherapy, current approaches are insufficient to stop the advance of the disease and many cancer types remain largely intractable. In this review, we describe the latest and most revolutionary stem cell-based approaches for the treatment of cancer. We also summarize the emerging imaging modalities being applied for monitoring anticancer stem cell therapy success and discuss the implications of these novel technologies for precision medicine.
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institution Kabale University
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spelling doaj-art-ee2f299102724ba788e8d73719ef5b072025-02-03T01:21:59ZengWileyStem Cells International1687-966X1687-96782018-01-01201810.1155/2018/73152187315218New Strategies and In Vivo Monitoring Methods for Stem Cell-Based Anticancer TherapiesPing Wang0Aitor Aguirre1Precision Health Program, Department of Radiology, College of Human Medicine, Michigan State University, East Lansing, MI 48823, USADivision of Developmental and Stem Cell Biology, Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI 48823, USACancer is a devastating disease and the second cause of death in the developed world. Despite significant advances in recent years, such as the introduction of targeted therapies such as receptor tyrosine kinase inhibitors and immunotherapy, current approaches are insufficient to stop the advance of the disease and many cancer types remain largely intractable. In this review, we describe the latest and most revolutionary stem cell-based approaches for the treatment of cancer. We also summarize the emerging imaging modalities being applied for monitoring anticancer stem cell therapy success and discuss the implications of these novel technologies for precision medicine.http://dx.doi.org/10.1155/2018/7315218
spellingShingle Ping Wang
Aitor Aguirre
New Strategies and In Vivo Monitoring Methods for Stem Cell-Based Anticancer Therapies
Stem Cells International
title New Strategies and In Vivo Monitoring Methods for Stem Cell-Based Anticancer Therapies
title_full New Strategies and In Vivo Monitoring Methods for Stem Cell-Based Anticancer Therapies
title_fullStr New Strategies and In Vivo Monitoring Methods for Stem Cell-Based Anticancer Therapies
title_full_unstemmed New Strategies and In Vivo Monitoring Methods for Stem Cell-Based Anticancer Therapies
title_short New Strategies and In Vivo Monitoring Methods for Stem Cell-Based Anticancer Therapies
title_sort new strategies and in vivo monitoring methods for stem cell based anticancer therapies
url http://dx.doi.org/10.1155/2018/7315218
work_keys_str_mv AT pingwang newstrategiesandinvivomonitoringmethodsforstemcellbasedanticancertherapies
AT aitoraguirre newstrategiesandinvivomonitoringmethodsforstemcellbasedanticancertherapies