Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation
A 15-year-old male admitted for Pott's puffy tumor developed recurrent episodes of fever, diffuse morbilliform rash, eosinophilia, and tubulointerstitial nephritis while on multiple antibiotics. Lymphocyte blast transformation (LBT), a method of detecting cellular immune response by measuring...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2011/562620 |
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| _version_ | 1832568043361796096 |
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| author | Nguyen P. Tran Jeremy Katcher Erin Rohman Mary Francis Hall Christie F. Michael Isao Miyairi D. Betty Lew |
| author_facet | Nguyen P. Tran Jeremy Katcher Erin Rohman Mary Francis Hall Christie F. Michael Isao Miyairi D. Betty Lew |
| author_sort | Nguyen P. Tran |
| collection | DOAJ |
| description | A 15-year-old male admitted for Pott's puffy tumor developed recurrent episodes of fever, diffuse morbilliform rash, eosinophilia, and tubulointerstitial nephritis while on multiple antibiotics. Lymphocyte blast transformation (LBT), a method of detecting cellular immune response by measuring levels of interferon-γ (IFN-γ), was used to diagnose vancomycin hypersensitivity and guide antibiotic selection. |
| format | Article |
| id | doaj-art-ee28ea4fde814278970bf8e493d2cf1d |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-ee28ea4fde814278970bf8e493d2cf1d2025-02-03T00:59:55ZengWileyCase Reports in Pediatrics2090-68032090-68112011-01-01201110.1155/2011/562620562620Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast TransformationNguyen P. Tran0Jeremy Katcher1Erin Rohman2Mary Francis Hall3Christie F. Michael4Isao Miyairi5D. Betty Lew6Allergy/Immunology, Le Bonheur Children's Hospital, Memphis, TN 38103, USAAllergy/Immunology, Le Bonheur Children's Hospital, Memphis, TN 38103, USAAllergy/Immunology, Le Bonheur Children's Hospital, Memphis, TN 38103, USADiagnostic Immunology, Memphis Pathology Laboratories, Memphis, TN 38141, USAAllergy/Immunology, Le Bonheur Children's Hospital, Memphis, TN 38103, USAAllergy/Immunology, Le Bonheur Children's Hospital, Memphis, TN 38103, USAAllergy/Immunology, Le Bonheur Children's Hospital, Memphis, TN 38103, USAA 15-year-old male admitted for Pott's puffy tumor developed recurrent episodes of fever, diffuse morbilliform rash, eosinophilia, and tubulointerstitial nephritis while on multiple antibiotics. Lymphocyte blast transformation (LBT), a method of detecting cellular immune response by measuring levels of interferon-γ (IFN-γ), was used to diagnose vancomycin hypersensitivity and guide antibiotic selection.http://dx.doi.org/10.1155/2011/562620 |
| spellingShingle | Nguyen P. Tran Jeremy Katcher Erin Rohman Mary Francis Hall Christie F. Michael Isao Miyairi D. Betty Lew Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation Case Reports in Pediatrics |
| title | Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation |
| title_full | Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation |
| title_fullStr | Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation |
| title_full_unstemmed | Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation |
| title_short | Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation |
| title_sort | vancomycin hypersensitivity diagnosed by lymphocyte blast transformation |
| url | http://dx.doi.org/10.1155/2011/562620 |
| work_keys_str_mv | AT nguyenptran vancomycinhypersensitivitydiagnosedbylymphocyteblasttransformation AT jeremykatcher vancomycinhypersensitivitydiagnosedbylymphocyteblasttransformation AT erinrohman vancomycinhypersensitivitydiagnosedbylymphocyteblasttransformation AT maryfrancishall vancomycinhypersensitivitydiagnosedbylymphocyteblasttransformation AT christiefmichael vancomycinhypersensitivitydiagnosedbylymphocyteblasttransformation AT isaomiyairi vancomycinhypersensitivitydiagnosedbylymphocyteblasttransformation AT dbettylew vancomycinhypersensitivitydiagnosedbylymphocyteblasttransformation |