Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome

Detection of right heart thrombi (RHT) in the context of pulmonary thromboembolism (PE) is uncommon (4–18%) and increases the risk of mortality beyond the presence of PE alone. Type A thrombi are serpiginous and highly mobile and are thought to be originated from large veins and captured in-transit...

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Main Authors: João Português, Lucy Calvo, Margarida Oliveira, Vítor Hugo Pereira, Joana Guardado, Mário Rui Lourenço, Olga Azevedo, Francisco Ferreira, Filipa Canário-Almeida, António Lourenço
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2017/9092576
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author João Português
Lucy Calvo
Margarida Oliveira
Vítor Hugo Pereira
Joana Guardado
Mário Rui Lourenço
Olga Azevedo
Francisco Ferreira
Filipa Canário-Almeida
António Lourenço
author_facet João Português
Lucy Calvo
Margarida Oliveira
Vítor Hugo Pereira
Joana Guardado
Mário Rui Lourenço
Olga Azevedo
Francisco Ferreira
Filipa Canário-Almeida
António Lourenço
author_sort João Português
collection DOAJ
description Detection of right heart thrombi (RHT) in the context of pulmonary thromboembolism (PE) is uncommon (4–18%) and increases the risk of mortality beyond the presence of PE alone. Type A thrombi are serpiginous and highly mobile and are thought to be originated from large veins and captured in-transit within the right heart. Optimal management of RHT is still uncertain. A 79-year-old woman, with a history of recent total hysterectomy with adnexectomy and a Wells procedure, presented to the emergency department following an episode of syncope. Computed tomography revealed bilateral PE and the presence of a right atrial thrombus. Transthoracic echocardiography demonstrated a free-floating type A thrombus in the right atrium, protruding into the right ventricle, and signs of pulmonary hypertension and right ventricle dysfunction. Considering the recent surgery and clinical stability, treatment with heparin alone was decided. Subsequent clinical improvement was observed and echocardiographic follow-up revealed complete thrombus dissolution and complete recovery of right ventricle function. Most authors recommend treatment of PE with RHT with thrombolysis or embolectomy followed by anticoagulation, although evidence is scarce. Individual risk of hemorrhage and operatory-related mortality should be taken into account when defining the treatment strategy especially when benefit is not firmly established.
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spelling doaj-art-ee0e61b3031d4112a24fb04e779bd4962025-02-03T05:43:43ZengWileyCase Reports in Cardiology2090-64042090-64122017-01-01201710.1155/2017/90925769092576Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected OutcomeJoão Português0Lucy Calvo1Margarida Oliveira2Vítor Hugo Pereira3Joana Guardado4Mário Rui Lourenço5Olga Azevedo6Francisco Ferreira7Filipa Canário-Almeida8António Lourenço9Cardiology Department, Hospital Senhora da Oliveira, Guimarães, PortugalCardiology Department, Hospital Senhora da Oliveira, Guimarães, PortugalCardiology Department, Hospital Senhora da Oliveira, Guimarães, PortugalEscola de Ciências da Saúde, Universidade do Minho, Braga, PortugalCardiology Department, Centro Hospitalar de Leiria, Leiria, PortugalCardiology Department, Hospital Senhora da Oliveira, Guimarães, PortugalCardiology Department, Hospital Senhora da Oliveira, Guimarães, PortugalCardiology Department, Hospital Senhora da Oliveira, Guimarães, PortugalCardiology Department, Hospital Senhora da Oliveira, Guimarães, PortugalCardiology Department, Hospital Senhora da Oliveira, Guimarães, PortugalDetection of right heart thrombi (RHT) in the context of pulmonary thromboembolism (PE) is uncommon (4–18%) and increases the risk of mortality beyond the presence of PE alone. Type A thrombi are serpiginous and highly mobile and are thought to be originated from large veins and captured in-transit within the right heart. Optimal management of RHT is still uncertain. A 79-year-old woman, with a history of recent total hysterectomy with adnexectomy and a Wells procedure, presented to the emergency department following an episode of syncope. Computed tomography revealed bilateral PE and the presence of a right atrial thrombus. Transthoracic echocardiography demonstrated a free-floating type A thrombus in the right atrium, protruding into the right ventricle, and signs of pulmonary hypertension and right ventricle dysfunction. Considering the recent surgery and clinical stability, treatment with heparin alone was decided. Subsequent clinical improvement was observed and echocardiographic follow-up revealed complete thrombus dissolution and complete recovery of right ventricle function. Most authors recommend treatment of PE with RHT with thrombolysis or embolectomy followed by anticoagulation, although evidence is scarce. Individual risk of hemorrhage and operatory-related mortality should be taken into account when defining the treatment strategy especially when benefit is not firmly established.http://dx.doi.org/10.1155/2017/9092576
spellingShingle João Português
Lucy Calvo
Margarida Oliveira
Vítor Hugo Pereira
Joana Guardado
Mário Rui Lourenço
Olga Azevedo
Francisco Ferreira
Filipa Canário-Almeida
António Lourenço
Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
Case Reports in Cardiology
title Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title_full Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title_fullStr Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title_full_unstemmed Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title_short Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title_sort pulmonary embolism and intracardiac type a thrombus with an unexpected outcome
url http://dx.doi.org/10.1155/2017/9092576
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