Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement
Background. ‘Maturity-Onset Diabetes of the Young’ (MODY) or monogenic diabetes accounts for approximately 1–2% of diabetes and is frequently misdiagnosed as type 1 or type 2 diabetes. Here we report a case of a 19-year-old pregnant woman with a MODY 3 diabetes expecting a child to a father with MOD...
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Format: | Article |
Language: | English |
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Wiley
2018-01-01
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Series: | Case Reports in Obstetrics and Gynecology |
Online Access: | http://dx.doi.org/10.1155/2018/9451061 |
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author | Anastasia Mikuscheva Adel Mekhail Benjamin J. Wheeler |
author_facet | Anastasia Mikuscheva Adel Mekhail Benjamin J. Wheeler |
author_sort | Anastasia Mikuscheva |
collection | DOAJ |
description | Background. ‘Maturity-Onset Diabetes of the Young’ (MODY) or monogenic diabetes accounts for approximately 1–2% of diabetes and is frequently misdiagnosed as type 1 or type 2 diabetes. Here we report a case of a 19-year-old pregnant woman with a MODY 3 diabetes expecting a child to a father with MODY 2 diabetes. Possible inheritance scenarios are described and the implications of these scenarios on the pregnancy and infant are discussed. In addition, the pregnancy was complicated by drastically falling insulin requirements in the mother in the 3rd trimester as well as preterm labour and delivery at 33+4 weeks of gestation. |
format | Article |
id | doaj-art-ededd9c9e22541e0842ef20105fcbe13 |
institution | Kabale University |
issn | 2090-6684 2090-6692 |
language | English |
publishDate | 2018-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Obstetrics and Gynecology |
spelling | doaj-art-ededd9c9e22541e0842ef20105fcbe132025-02-03T05:52:18ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922018-01-01201810.1155/2018/94510619451061Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin RequirementAnastasia Mikuscheva0Adel Mekhail1Benjamin J. Wheeler2Gynecology and Obstetrics, Southern District Health Board, Dunedin, New ZealandGynecology and Obstetrics, Southern District Health Board, Dunedin, New ZealandDepartment of Women’s and Children’s Health, University of Otago, Dunedin, New ZealandBackground. ‘Maturity-Onset Diabetes of the Young’ (MODY) or monogenic diabetes accounts for approximately 1–2% of diabetes and is frequently misdiagnosed as type 1 or type 2 diabetes. Here we report a case of a 19-year-old pregnant woman with a MODY 3 diabetes expecting a child to a father with MODY 2 diabetes. Possible inheritance scenarios are described and the implications of these scenarios on the pregnancy and infant are discussed. In addition, the pregnancy was complicated by drastically falling insulin requirements in the mother in the 3rd trimester as well as preterm labour and delivery at 33+4 weeks of gestation.http://dx.doi.org/10.1155/2018/9451061 |
spellingShingle | Anastasia Mikuscheva Adel Mekhail Benjamin J. Wheeler Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement Case Reports in Obstetrics and Gynecology |
title | Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement |
title_full | Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement |
title_fullStr | Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement |
title_full_unstemmed | Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement |
title_short | Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement |
title_sort | pregnancy complicated by maternal mody 3 and paternal mody 2 diabetes and subsequent rapidly falling insulin requirement |
url | http://dx.doi.org/10.1155/2018/9451061 |
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