Sex differences in delivery and neonatal characteristics of new-borns from the “MAMI-MED” cohort
IntroductionExploring modifiable and non-modifiable determinants—like sex of new-borns, maternal characteristics, and lifestyle—of maternal and child health is a priority in Public Health. Understanding these sex-based differences is essential for tailored care and informed public health policies.Me...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1498125/full |
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| author | Roberta Magnano San Lio Martina Barchitta Andrea Maugeri Elisabetta Campisi Giuliana Favara Claudia Ojeda Granados Claudia La Mastra Maria Clara La Rosa Fabiola Galvani Elisa Pappalardo Carla Ettore Giuseppe Ettore Antonella Agodi |
| author_facet | Roberta Magnano San Lio Martina Barchitta Andrea Maugeri Elisabetta Campisi Giuliana Favara Claudia Ojeda Granados Claudia La Mastra Maria Clara La Rosa Fabiola Galvani Elisa Pappalardo Carla Ettore Giuseppe Ettore Antonella Agodi |
| author_sort | Roberta Magnano San Lio |
| collection | DOAJ |
| description | IntroductionExploring modifiable and non-modifiable determinants—like sex of new-borns, maternal characteristics, and lifestyle—of maternal and child health is a priority in Public Health. Understanding these sex-based differences is essential for tailored care and informed public health policies.MethodsThe present study aimed to delineate sex disparities in delivery and neonatal characteristics within the “MAMI MED” cohort, an ongoing prospective study involving mother–child pairs from Catania, Italy. The analysis included 1,090 mother–child pairs.ResultsThe comparison of birth weight and birth length distribution showed some differences between sexes, confirmed by higher birth weight (β = 0.121; 95% CI = 0.071–0.172) and greater birth length (β = 0.659; 95% CI = 0.360–0.958) in males compared to females. However, the comparison of small and adequate for gestational age (SGA vs. AGA) revealed that the likelihood of being SGA was higher in males than in females (OR = 1.592; 95% CI = 1.005–2.563).DiscussionThus, the focus should be on improving the assessment of gender-based differences in diagnostic criteria and incorporating gender-specific aspects into existing preventive guidelines to deeply understand the effect of gender disparities and risk factors on maternal-child health. |
| format | Article |
| id | doaj-art-ede2a21a5bb442e0bf72b916ee0565a4 |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Public Health |
| spelling | doaj-art-ede2a21a5bb442e0bf72b916ee0565a42025-01-27T11:25:22ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-01-011310.3389/fpubh.2025.14981251498125Sex differences in delivery and neonatal characteristics of new-borns from the “MAMI-MED” cohortRoberta Magnano San Lio0Martina Barchitta1Andrea Maugeri2Elisabetta Campisi3Giuliana Favara4Claudia Ojeda Granados5Claudia La Mastra6Maria Clara La Rosa7Fabiola Galvani8Elisa Pappalardo9Carla Ettore10Giuseppe Ettore11Antonella Agodi12Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, ItalyDepartment of Obstetrics and Gynaecology, Azienda di Rilievo Nazionale e di Alta Specializzazione (ARNAS) Garibaldi Nesima, Catania, ItalyDepartment of Obstetrics and Gynaecology, Azienda di Rilievo Nazionale e di Alta Specializzazione (ARNAS) Garibaldi Nesima, Catania, ItalyDepartment of Obstetrics and Gynaecology, Azienda di Rilievo Nazionale e di Alta Specializzazione (ARNAS) Garibaldi Nesima, Catania, ItalyDepartment of Obstetrics and Gynaecology, Azienda di Rilievo Nazionale e di Alta Specializzazione (ARNAS) Garibaldi Nesima, Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, ItalyIntroductionExploring modifiable and non-modifiable determinants—like sex of new-borns, maternal characteristics, and lifestyle—of maternal and child health is a priority in Public Health. Understanding these sex-based differences is essential for tailored care and informed public health policies.MethodsThe present study aimed to delineate sex disparities in delivery and neonatal characteristics within the “MAMI MED” cohort, an ongoing prospective study involving mother–child pairs from Catania, Italy. The analysis included 1,090 mother–child pairs.ResultsThe comparison of birth weight and birth length distribution showed some differences between sexes, confirmed by higher birth weight (β = 0.121; 95% CI = 0.071–0.172) and greater birth length (β = 0.659; 95% CI = 0.360–0.958) in males compared to females. However, the comparison of small and adequate for gestational age (SGA vs. AGA) revealed that the likelihood of being SGA was higher in males than in females (OR = 1.592; 95% CI = 1.005–2.563).DiscussionThus, the focus should be on improving the assessment of gender-based differences in diagnostic criteria and incorporating gender-specific aspects into existing preventive guidelines to deeply understand the effect of gender disparities and risk factors on maternal-child health.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1498125/fullpregnancysex differencesneonatal outcomesbirth weightweight for gestational agematernal health |
| spellingShingle | Roberta Magnano San Lio Martina Barchitta Andrea Maugeri Elisabetta Campisi Giuliana Favara Claudia Ojeda Granados Claudia La Mastra Maria Clara La Rosa Fabiola Galvani Elisa Pappalardo Carla Ettore Giuseppe Ettore Antonella Agodi Sex differences in delivery and neonatal characteristics of new-borns from the “MAMI-MED” cohort Frontiers in Public Health pregnancy sex differences neonatal outcomes birth weight weight for gestational age maternal health |
| title | Sex differences in delivery and neonatal characteristics of new-borns from the “MAMI-MED” cohort |
| title_full | Sex differences in delivery and neonatal characteristics of new-borns from the “MAMI-MED” cohort |
| title_fullStr | Sex differences in delivery and neonatal characteristics of new-borns from the “MAMI-MED” cohort |
| title_full_unstemmed | Sex differences in delivery and neonatal characteristics of new-borns from the “MAMI-MED” cohort |
| title_short | Sex differences in delivery and neonatal characteristics of new-borns from the “MAMI-MED” cohort |
| title_sort | sex differences in delivery and neonatal characteristics of new borns from the mami med cohort |
| topic | pregnancy sex differences neonatal outcomes birth weight weight for gestational age maternal health |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1498125/full |
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