When the mask slips: A peripheral T-cell lymphoma disguised as lupus with myelofibrosis in a patient with May-Hegglin syndrome
We describe the case of a female patient with May-Hegglin syndrome who developed peripheral T-cell lymphoma not otherwise specified. The patient presents with systemic lupus erythematous phenotype and myelofibrosis secondary to T-cell lymphoma. Peripheral T-cell lymphoma not otherwise specified, rep...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Leukemia Research Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213048924000888 |
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| author | V Da Silva Constante H Couvert A Wolfromm M Ilzkovitz |
| author_facet | V Da Silva Constante H Couvert A Wolfromm M Ilzkovitz |
| author_sort | V Da Silva Constante |
| collection | DOAJ |
| description | We describe the case of a female patient with May-Hegglin syndrome who developed peripheral T-cell lymphoma not otherwise specified. The patient presents with systemic lupus erythematous phenotype and myelofibrosis secondary to T-cell lymphoma. Peripheral T-cell lymphoma not otherwise specified, represents 25 % of all peripheral T-cell lymphoma. Its diagnosis remains challenging due to the polymorphous clinical presentation and pathological heterogeneity. Myelofibrosis associated with malignant lymphomas is rare and peripheral T-cell lymphoma is even rarer. To our knowledge, this is the first case to describe an association between May-Hegglin syndrome and a peripheral T-cell lymphoma. |
| format | Article |
| id | doaj-art-edce5c3473014f4ea698204443e48aef |
| institution | Kabale University |
| issn | 2213-0489 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Leukemia Research Reports |
| spelling | doaj-art-edce5c3473014f4ea698204443e48aef2025-08-20T03:30:47ZengElsevierLeukemia Research Reports2213-04892025-01-012310049810.1016/j.lrr.2024.100498When the mask slips: A peripheral T-cell lymphoma disguised as lupus with myelofibrosis in a patient with May-Hegglin syndromeV Da Silva Constante0H Couvert1A Wolfromm2M Ilzkovitz3Hematology Department, Institut Jules Bordet – Hôpital Universitaire de Bruxelles (H.U.B.), Université Libre de Bruxelles (ULB), Brussels, BelgiumInternal Medicine Department, Institut Jules Bordet – Hôpital Universitaire de Bruxelles (H.U.B.), Université Libre de Bruxelles (ULB), Brussels, BelgiumHematology Department, Institut Jules Bordet – Hôpital Universitaire de Bruxelles (H.U.B.), Université Libre de Bruxelles (ULB), Brussels, BelgiumInternal Medicine Department, Institut Jules Bordet – Hôpital Universitaire de Bruxelles (H.U.B.), Université Libre de Bruxelles (ULB), Brussels, Belgium; Corresponding author at: Hôpital Universitaire de Bruxelles (H.U.B.), Université Libre de Bruxelles (ULB), Brussels Belgium. Rue Meylemeersch 90, 1070 Anderlecht- Brussels, Belgium.We describe the case of a female patient with May-Hegglin syndrome who developed peripheral T-cell lymphoma not otherwise specified. The patient presents with systemic lupus erythematous phenotype and myelofibrosis secondary to T-cell lymphoma. Peripheral T-cell lymphoma not otherwise specified, represents 25 % of all peripheral T-cell lymphoma. Its diagnosis remains challenging due to the polymorphous clinical presentation and pathological heterogeneity. Myelofibrosis associated with malignant lymphomas is rare and peripheral T-cell lymphoma is even rarer. To our knowledge, this is the first case to describe an association between May-Hegglin syndrome and a peripheral T-cell lymphoma.http://www.sciencedirect.com/science/article/pii/S2213048924000888Peripheral T-cell lymphomaPTCL, NOSMyelofibrosisSystemic lupus erythematosusMay-Hegglin syndrome |
| spellingShingle | V Da Silva Constante H Couvert A Wolfromm M Ilzkovitz When the mask slips: A peripheral T-cell lymphoma disguised as lupus with myelofibrosis in a patient with May-Hegglin syndrome Leukemia Research Reports Peripheral T-cell lymphoma PTCL, NOS Myelofibrosis Systemic lupus erythematosus May-Hegglin syndrome |
| title | When the mask slips: A peripheral T-cell lymphoma disguised as lupus with myelofibrosis in a patient with May-Hegglin syndrome |
| title_full | When the mask slips: A peripheral T-cell lymphoma disguised as lupus with myelofibrosis in a patient with May-Hegglin syndrome |
| title_fullStr | When the mask slips: A peripheral T-cell lymphoma disguised as lupus with myelofibrosis in a patient with May-Hegglin syndrome |
| title_full_unstemmed | When the mask slips: A peripheral T-cell lymphoma disguised as lupus with myelofibrosis in a patient with May-Hegglin syndrome |
| title_short | When the mask slips: A peripheral T-cell lymphoma disguised as lupus with myelofibrosis in a patient with May-Hegglin syndrome |
| title_sort | when the mask slips a peripheral t cell lymphoma disguised as lupus with myelofibrosis in a patient with may hegglin syndrome |
| topic | Peripheral T-cell lymphoma PTCL, NOS Myelofibrosis Systemic lupus erythematosus May-Hegglin syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S2213048924000888 |
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