Development of several machine learning based models for determination of small molecule pharmaceutical solubility in binary solvents at different temperatures

Abstract Analysis of small-molecule drug solubility in binary solvents at different temperatures was carried out via several machine learning models and integration of models to optimize. We investigated the solubility of rivaroxaban in both dichloromethane and a variety of primary alcohols at vario...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohammed Alqarni, Ali Alqarni
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-13090-4
Tags: Add Tag
No Tags, Be the first to tag this record!