Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes

As far as we know, no report uses the Swenson transanal endorectal pull-through technique in an animal model. Our objective is to describe the use of this technique as an experimental model for training and research purposes. Ten Norfolk hybrid rabbits were randomly selected from our experimental la...

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Main Authors: Maria Luiza Gandra de Meira, Renata Buraschi Antunes, Vitoria de Oliveira Zani, Gustavo Dutra de Oliveira, Diego Generoso, Erika Veruska Paiva Ortolan, Pedro Luiz Toledo de Arruda Lourenção
Format: Article
Language:English
Published: Taylor & Francis Group 2024-01-01
Series:Journal of Investigative Surgery
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Online Access:https://www.tandfonline.com/doi/10.1080/08941939.2024.2376548
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author Maria Luiza Gandra de Meira
Renata Buraschi Antunes
Vitoria de Oliveira Zani
Gustavo Dutra de Oliveira
Diego Generoso
Erika Veruska Paiva Ortolan
Pedro Luiz Toledo de Arruda Lourenção
author_facet Maria Luiza Gandra de Meira
Renata Buraschi Antunes
Vitoria de Oliveira Zani
Gustavo Dutra de Oliveira
Diego Generoso
Erika Veruska Paiva Ortolan
Pedro Luiz Toledo de Arruda Lourenção
author_sort Maria Luiza Gandra de Meira
collection DOAJ
description As far as we know, no report uses the Swenson transanal endorectal pull-through technique in an animal model. Our objective is to describe the use of this technique as an experimental model for training and research purposes. Ten Norfolk hybrid rabbits were randomly selected from our experimental laboratory, with a mean weight of 3539.3 (± 678.4) g. Neither colon preparation nor fast were used before the procedures. The surgical technique was based on the description performed by Levitt et al. (2013, J Pediatr Surg. 2013;48(11):2289–2295). Information related to the surgical procedures and the clinical evolution in the postoperative period were recorded and analyzed. There were no deaths or severe complications. The anesthetic and the surgical times were significantly higher for the first three animals of the experiment. Our animal model proved adequate to perform the transanal endorectal Swenson pull-through technique, allowing the training of surgical skills through a model similar to the human, with few anesthetic complications and good postoperative evolution, including postoperative follow-up. We believe that it will serve as a learning tool in many institutions that are continuously searching for improved new techniques and will support new researches in this area.
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spelling doaj-art-edca2fcc760d4e63b985e59a8d30d5942025-08-20T01:57:39ZengTaylor & Francis GroupJournal of Investigative Surgery0894-19391521-05532024-01-0137110.1080/08941939.2024.2376548Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research PurposesMaria Luiza Gandra de Meira0Renata Buraschi Antunes1Vitoria de Oliveira Zani2Gustavo Dutra de Oliveira3Diego Generoso4Erika Veruska Paiva Ortolan5Pedro Luiz Toledo de Arruda Lourenção6Division of Pediatric Surgery – Department of Surgery and Orthopedics – Faculty of Medicine of Botucatu – São Paulo State University (UNESP), Botucatu, BrazilDivision of Pediatric Surgery – Department of Surgery and Orthopedics – Faculty of Medicine of Botucatu – São Paulo State University (UNESP), Botucatu, BrazilDivision of Pediatric Surgery – Department of Surgery and Orthopedics – Faculty of Medicine of Botucatu – São Paulo State University (UNESP), Botucatu, BrazilDivision of Pediatric Surgery – Department of Surgery and Orthopedics – Faculty of Medicine of Botucatu – São Paulo State University (UNESP), Botucatu, BrazilExperimental Research Unit (UNIPEX) – Faculty of Medicine of Botucatu – São Paulo State University (UNESP), Botucatu, BrazilDivision of Pediatric Surgery – Department of Surgery and Orthopedics – Faculty of Medicine of Botucatu – São Paulo State University (UNESP), Botucatu, BrazilDivision of Pediatric Surgery – Department of Surgery and Orthopedics – Faculty of Medicine of Botucatu – São Paulo State University (UNESP), Botucatu, BrazilAs far as we know, no report uses the Swenson transanal endorectal pull-through technique in an animal model. Our objective is to describe the use of this technique as an experimental model for training and research purposes. Ten Norfolk hybrid rabbits were randomly selected from our experimental laboratory, with a mean weight of 3539.3 (± 678.4) g. Neither colon preparation nor fast were used before the procedures. The surgical technique was based on the description performed by Levitt et al. (2013, J Pediatr Surg. 2013;48(11):2289–2295). Information related to the surgical procedures and the clinical evolution in the postoperative period were recorded and analyzed. There were no deaths or severe complications. The anesthetic and the surgical times were significantly higher for the first three animals of the experiment. Our animal model proved adequate to perform the transanal endorectal Swenson pull-through technique, allowing the training of surgical skills through a model similar to the human, with few anesthetic complications and good postoperative evolution, including postoperative follow-up. We believe that it will serve as a learning tool in many institutions that are continuously searching for improved new techniques and will support new researches in this area.https://www.tandfonline.com/doi/10.1080/08941939.2024.2376548Hirschsprung diseaseexperimental modelsurgeryendorectal pull throughSwenson procedure
spellingShingle Maria Luiza Gandra de Meira
Renata Buraschi Antunes
Vitoria de Oliveira Zani
Gustavo Dutra de Oliveira
Diego Generoso
Erika Veruska Paiva Ortolan
Pedro Luiz Toledo de Arruda Lourenção
Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes
Journal of Investigative Surgery
Hirschsprung disease
experimental model
surgery
endorectal pull through
Swenson procedure
title Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes
title_full Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes
title_fullStr Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes
title_full_unstemmed Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes
title_short Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes
title_sort developing an animal model for swenson transanal endorectal pull through a new possibility for training and research purposes
topic Hirschsprung disease
experimental model
surgery
endorectal pull through
Swenson procedure
url https://www.tandfonline.com/doi/10.1080/08941939.2024.2376548
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