Lactoferrin-modified nanoemulsions enhance brain-targeting and therapeutic efficacy of arctigenin against Toxoplasma gondii-induced neuronal injury

Lactoferrin-modified nanoemulsions enhance brain-targeting and therapeutic efficacy of arctigenin against Toxoplasma gondii-induced neuronal injury

Toxoplasma gondii, a neurotropic protozoan parasite, affects the central nervous system and causes various neurological disorders. Previous studies have demonstrated that Arctigenin (AG) exhibits anti-T. gondii activity and reduces depression-like behaviors induced by T. gondii infection. This study...

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Bibliographic Details
Main Authors: Jing-Mei Lu, Guang-Nan Jin, Yan Xin, Jing-Wen Ma, Xin-Yu Shen, Yan-Zhu Quan, Yi-Ming Liu, Jin-Yi Zhou, Bing-Zhe Wang, Ying-Biao Li, Xiang Xu, Lian-Xun Piao
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Arctigenin
Lactoferrin
Nanoemulsions
Toxoplasma gondii
Neuron
Microglia
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320724000563
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