Dapagliflozin inhibits ferroptosis to improve chronic heart failure by regulating Nrf2/HO-1/GPX4 signaling pathway.

Dapagliflozin inhibits ferroptosis to improve chronic heart failure by regulating Nrf2/HO-1/GPX4 signaling pathway.

<h4>Objective</h4>To study the effect of Dapagliflozin on ferroptosis in rabbits with chronic heart failure and to reveal its possible mechanism.<h4>Methods</h4>Nine healthy adult male New Zealand white rabbits were randomly divided into Sham group (only thorax opening was pe...

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Bibliographic Details
Main Authors:	Jing Zhang, Xuefeng Chen, Shilin Lv, Qingqing Hao
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0317295
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