Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report

Basal cell carcinoma (BCC) is the most common skin cancer, and its incidence is increasing. Though metastatic BCC (mBCC) is uncommon, the literature demonstrates a 0.0028%-0.55% rate of metastasis. We report on a patient treated at our institution who was found to have mBCC with osseous metastases....

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Main Authors: Brianna R. Fram, John Strony, Geetha Jagannathan, Scot A. Brown
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2019/1628980
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author Brianna R. Fram
John Strony
Geetha Jagannathan
Scot A. Brown
author_facet Brianna R. Fram
John Strony
Geetha Jagannathan
Scot A. Brown
author_sort Brianna R. Fram
collection DOAJ
description Basal cell carcinoma (BCC) is the most common skin cancer, and its incidence is increasing. Though metastatic BCC (mBCC) is uncommon, the literature demonstrates a 0.0028%-0.55% rate of metastasis. We report on a patient treated at our institution who was found to have mBCC with osseous metastases. To our knowledge, this is the first report of mBCC in the orthopaedic literature. Orthopaedic oncologists should consider mBCC in patients diagnosed with carcinoma of unknown origin, with a known history of BCC, or individuals with light skin pigmentation and age 50 or greater. This can help clinicians make the correct diagnosis and provide the appropriate treatment.
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series Case Reports in Orthopedics
spelling doaj-art-ed9726d5cd8b4a7dbe2661cbfbde00292025-02-03T01:30:16ZengWileyCase Reports in Orthopedics2090-67492090-67572019-01-01201910.1155/2019/16289801628980Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case ReportBrianna R. Fram0John Strony1Geetha Jagannathan2Scot A. Brown3Department of Orthopaedic Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USARothman Orthopaedic Institute, Philadelphia, PA, USADepartment of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University Hospital, Philadelphia, PA, USARothman Orthopaedic Institute, Philadelphia, PA, USABasal cell carcinoma (BCC) is the most common skin cancer, and its incidence is increasing. Though metastatic BCC (mBCC) is uncommon, the literature demonstrates a 0.0028%-0.55% rate of metastasis. We report on a patient treated at our institution who was found to have mBCC with osseous metastases. To our knowledge, this is the first report of mBCC in the orthopaedic literature. Orthopaedic oncologists should consider mBCC in patients diagnosed with carcinoma of unknown origin, with a known history of BCC, or individuals with light skin pigmentation and age 50 or greater. This can help clinicians make the correct diagnosis and provide the appropriate treatment.http://dx.doi.org/10.1155/2019/1628980
spellingShingle Brianna R. Fram
John Strony
Geetha Jagannathan
Scot A. Brown
Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report
Case Reports in Orthopedics
title Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report
title_full Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report
title_fullStr Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report
title_full_unstemmed Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report
title_short Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report
title_sort cutaneous basal cell carcinoma with bone metastases an orthopaedic case report
url http://dx.doi.org/10.1155/2019/1628980
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