LEPTIN SERUM LEVEL IN WOMEN WITH OBESITY DO NOT DEFINE LEPTIN CORD BLOOD LEVEL IN THEIR NEWBORNS

Aim. To investigate the serum leptin level in pregnant women either with or without obesity and in their newborns. Materials and Methods. We examined 60 pregnant women with or without obesity (n = 30 per each group) at 38-40 weeks’ gestation along with their newborns following measurement of...

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Main Authors: OLGA B. Karelina, NATALIA V. Artymuk
Format: Article
Language:Russian
Published: Kemerovo State Medical University 2017-09-01
Series:Фундаментальная и клиническая медицина
Subjects:
Online Access:https://fcm.kemsmu.ru/jour/article/view/52
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author OLGA B. Karelina
NATALIA V. Artymuk
author_facet OLGA B. Karelina
NATALIA V. Artymuk
author_sort OLGA B. Karelina
collection DOAJ
description Aim. To investigate the serum leptin level in pregnant women either with or without obesity and in their newborns. Materials and Methods. We examined 60 pregnant women with or without obesity (n = 30 per each group) at 38-40 weeks’ gestation along with their newborns following measurement of serum and cord blood leptin level using an enzyme-linked immunosorbent assay.Results. Leptin serum level was significantly higher in obese women compared to those with a normal body weight. Strikingly, the cord blood level of leptin in newborns was lower than in their mothers and did not depend on either maternal body weight or maternal serum leptin level. Conclusions. Serum leptin level in pregnant women is determined by the body weight but does not define cord blood level of leptin in their newborns.
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language Russian
publishDate 2017-09-01
publisher Kemerovo State Medical University
record_format Article
series Фундаментальная и клиническая медицина
spelling doaj-art-ed8ed71d3c8d4e8da9d910c51fdbc5ea2025-08-20T03:19:11ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412017-09-0123212751LEPTIN SERUM LEVEL IN WOMEN WITH OBESITY DO NOT DEFINE LEPTIN CORD BLOOD LEVEL IN THEIR NEWBORNSOLGA B. Karelina0NATALIA V. Artymuk1Kemerovo State Medical UniversityKemerovo State Medical UniversityAim. To investigate the serum leptin level in pregnant women either with or without obesity and in their newborns. Materials and Methods. We examined 60 pregnant women with or without obesity (n = 30 per each group) at 38-40 weeks’ gestation along with their newborns following measurement of serum and cord blood leptin level using an enzyme-linked immunosorbent assay.Results. Leptin serum level was significantly higher in obese women compared to those with a normal body weight. Strikingly, the cord blood level of leptin in newborns was lower than in their mothers and did not depend on either maternal body weight or maternal serum leptin level. Conclusions. Serum leptin level in pregnant women is determined by the body weight but does not define cord blood level of leptin in their newborns.https://fcm.kemsmu.ru/jour/article/view/52ожирениелептинноворожденныеobesityleptinnewborns
spellingShingle OLGA B. Karelina
NATALIA V. Artymuk
LEPTIN SERUM LEVEL IN WOMEN WITH OBESITY DO NOT DEFINE LEPTIN CORD BLOOD LEVEL IN THEIR NEWBORNS
Фундаментальная и клиническая медицина
ожирение
лептин
новорожденные
obesity
leptin
newborns
title LEPTIN SERUM LEVEL IN WOMEN WITH OBESITY DO NOT DEFINE LEPTIN CORD BLOOD LEVEL IN THEIR NEWBORNS
title_full LEPTIN SERUM LEVEL IN WOMEN WITH OBESITY DO NOT DEFINE LEPTIN CORD BLOOD LEVEL IN THEIR NEWBORNS
title_fullStr LEPTIN SERUM LEVEL IN WOMEN WITH OBESITY DO NOT DEFINE LEPTIN CORD BLOOD LEVEL IN THEIR NEWBORNS
title_full_unstemmed LEPTIN SERUM LEVEL IN WOMEN WITH OBESITY DO NOT DEFINE LEPTIN CORD BLOOD LEVEL IN THEIR NEWBORNS
title_short LEPTIN SERUM LEVEL IN WOMEN WITH OBESITY DO NOT DEFINE LEPTIN CORD BLOOD LEVEL IN THEIR NEWBORNS
title_sort leptin serum level in women with obesity do not define leptin cord blood level in their newborns
topic ожирение
лептин
новорожденные
obesity
leptin
newborns
url https://fcm.kemsmu.ru/jour/article/view/52
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AT nataliavartymuk leptinserumlevelinwomenwithobesitydonotdefineleptincordbloodlevelintheirnewborns