Modulation of oxazolone-induced hypersensitivity in mice by selective PDE inhibitors
The effects of PDE inhibitors on oxazolone-induced contact hypersensitivity (CS) were studied in mice. Rolipram, Ro 20-1724 and theophylline dose dependently inhibited CS but none caused >53% inhibition. ED30 values at 24 h before challenge for rolipram, Ro 20-1724 and theophylline were 2.1, 5.4...
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Main Authors: | I. Moodley, Y. Sotsios, B. Bertin |
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Format: | Article |
Language: | English |
Published: |
Wiley
1995-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/S0962935195000196 |
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