Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care Patient
Unrecognized severe pseudomembranous colitis may become life threatening. A typical Clostridium difficile infection is associated with involvement of the colon; however, small bowel disease has also been described. Here, we present a case of a 48-year-old man with Clostridium difficile colitis of an...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2012/482930 |
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| author | Evgeni Brotfain Leonid Koyfman Amit Frenkel Jochanan G. Peiser Abraham Borer Benjamin F. Gruenbaum Alexander Zlotnik Moti Klein |
| author_facet | Evgeni Brotfain Leonid Koyfman Amit Frenkel Jochanan G. Peiser Abraham Borer Benjamin F. Gruenbaum Alexander Zlotnik Moti Klein |
| author_sort | Evgeni Brotfain |
| collection | DOAJ |
| description | Unrecognized severe pseudomembranous colitis may become life threatening. A typical Clostridium difficile infection is associated with involvement of the colon; however, small bowel disease has also been described. Here, we present a case of a 48-year-old man with Clostridium difficile colitis of an isolated segment in the descending colon treated by a novel catheter intraluminal antibiotic irrigation. The intraluminal antibiotic irrigation was performed through a Foley catheter inserted into the isolated mucus fistula. The patient recovered after three weeks of intraluminal vancomycin (250 mg diluted in 150 ml of normal saline x Q6) and metronidazole (500 mg x Q8). Both antibiotics were given into the mucus fistula over 30 min. The patient was discharged from the unit four weeks after admission. This novel technique, in which the antibiotic was administered through an inserted intraluminal Foley urinary catheter, may be an efficient and safe alternative when conventional routes cannot be implemented. |
| format | Article |
| id | doaj-art-ed5ef08bf5104bdd95bfe532daed0a45 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-ed5ef08bf5104bdd95bfe532daed0a452025-02-03T01:11:08ZengWileyCase Reports in Surgery2090-69002090-69192012-01-01201210.1155/2012/482930482930Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care PatientEvgeni Brotfain0Leonid Koyfman1Amit Frenkel2Jochanan G. Peiser3Abraham Borer4Benjamin F. Gruenbaum5Alexander Zlotnik6Moti Klein7Department of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 84105 Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 84105 Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 84105 Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 84105 Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 84105 Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 84105 Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 84105 Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 84105 Beer Sheva, IsraelUnrecognized severe pseudomembranous colitis may become life threatening. A typical Clostridium difficile infection is associated with involvement of the colon; however, small bowel disease has also been described. Here, we present a case of a 48-year-old man with Clostridium difficile colitis of an isolated segment in the descending colon treated by a novel catheter intraluminal antibiotic irrigation. The intraluminal antibiotic irrigation was performed through a Foley catheter inserted into the isolated mucus fistula. The patient recovered after three weeks of intraluminal vancomycin (250 mg diluted in 150 ml of normal saline x Q6) and metronidazole (500 mg x Q8). Both antibiotics were given into the mucus fistula over 30 min. The patient was discharged from the unit four weeks after admission. This novel technique, in which the antibiotic was administered through an inserted intraluminal Foley urinary catheter, may be an efficient and safe alternative when conventional routes cannot be implemented.http://dx.doi.org/10.1155/2012/482930 |
| spellingShingle | Evgeni Brotfain Leonid Koyfman Amit Frenkel Jochanan G. Peiser Abraham Borer Benjamin F. Gruenbaum Alexander Zlotnik Moti Klein Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care Patient Case Reports in Surgery |
| title | Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care Patient |
| title_full | Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care Patient |
| title_fullStr | Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care Patient |
| title_full_unstemmed | Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care Patient |
| title_short | Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care Patient |
| title_sort | unusual localization of clostridium difficile infection in an isolated segment of the descending colon in a critical care patient |
| url | http://dx.doi.org/10.1155/2012/482930 |
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