Association between polymorphisms of glucagon-like peptide-1 receptor gene and susceptibility to osteoporosis in Chinese postmenopausal women

Association between polymorphisms of glucagon-like peptide-1 receptor gene and susceptibility to osteoporosis in Chinese postmenopausal women

Abstract Background The influence of the glucagon-like peptide-1 receptor (GLP-1R) on bone metabolism is well-established. However, it has been observed that single nucleotide polymorphisms (SNPs) in the GLP-1R gene can partially affect its function. Therefore, this study aims to investigate the ass...

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Bibliographic Details
Main Authors: Xiaoxue Bao, Chang Liu, Huiming Liu, Yan Wang, Peng Xue, Yukun Li
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Glucagon-like peptide-1 receptor
Single-nucleotide polymorphism
Postmenopausal osteoporosis
Haplotype
Bone mineral density
Online Access:https://doi.org/10.1186/s13018-024-05361-z
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