Chromosome-level genome assembly of Nothapodytes nimmoniana

Abstract Nothapodytes nimmoniana is a plant species belonging to the genus Nothapodytes in the family Icacinaceae. This species holds significant medicinal value due to its camptothecin content. In this study, we present the first chromosome-level genome assembly of N. nimmoniana constructed using N...

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Main Authors: Jiahui Wang, Xiaojie Ma, Xingyu Yang, Danni Yang, Tianping Huang, Yunqiang Yang, Yongping Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-05484-w
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author Jiahui Wang
Xiaojie Ma
Xingyu Yang
Danni Yang
Tianping Huang
Yunqiang Yang
Yongping Yang
author_facet Jiahui Wang
Xiaojie Ma
Xingyu Yang
Danni Yang
Tianping Huang
Yunqiang Yang
Yongping Yang
author_sort Jiahui Wang
collection DOAJ
description Abstract Nothapodytes nimmoniana is a plant species belonging to the genus Nothapodytes in the family Icacinaceae. This species holds significant medicinal value due to its camptothecin content. In this study, we present the first chromosome-level genome assembly of N. nimmoniana constructed using NGS, Hi-C, and HiFi sequencing technologies. The assembled genome spans 3.53 Gb across 14 chromosomes, with an N50 length of 248.74 Mb. Genome annotation revealed that repetitive sequences constitute 80.82% of the genome size, and 83,269 protein-coding genes were predicted. Additionally, 4,360,538 bp of non-coding RNA were annotated. This genomic resource provides a foundation for further investigation into camptothecin biosynthesis pathways and plant phylogeny in N. nimmoniana.
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series Scientific Data
spelling doaj-art-ed3e7ed413a047ba8ddf13dfd068dd8a2025-08-20T03:45:45ZengNature PortfolioScientific Data2052-44632025-07-011211810.1038/s41597-025-05484-wChromosome-level genome assembly of Nothapodytes nimmonianaJiahui Wang0Xiaojie Ma1Xingyu Yang2Danni Yang3Tianping Huang4Yunqiang Yang5Yongping Yang6Yunnan International Joint Laboratory for the Conservation and Utilization of Tropical Timber Tree Species, Xishuangbanna Tropical Botanical Garden, Chinese Academy of SciencesYunnan International Joint Laboratory for the Conservation and Utilization of Tropical Timber Tree Species, Xishuangbanna Tropical Botanical Garden, Chinese Academy of SciencesYunnan International Joint Laboratory for the Conservation and Utilization of Tropical Timber Tree Species, Xishuangbanna Tropical Botanical Garden, Chinese Academy of SciencesYunnan International Joint Laboratory for the Conservation and Utilization of Tropical Timber Tree Species, Xishuangbanna Tropical Botanical Garden, Chinese Academy of SciencesYunnan International Joint Laboratory for the Conservation and Utilization of Tropical Timber Tree Species, Xishuangbanna Tropical Botanical Garden, Chinese Academy of SciencesYunnan International Joint Laboratory for the Conservation and Utilization of Tropical Timber Tree Species, Xishuangbanna Tropical Botanical Garden, Chinese Academy of SciencesYunnan International Joint Laboratory for the Conservation and Utilization of Tropical Timber Tree Species, Xishuangbanna Tropical Botanical Garden, Chinese Academy of SciencesAbstract Nothapodytes nimmoniana is a plant species belonging to the genus Nothapodytes in the family Icacinaceae. This species holds significant medicinal value due to its camptothecin content. In this study, we present the first chromosome-level genome assembly of N. nimmoniana constructed using NGS, Hi-C, and HiFi sequencing technologies. The assembled genome spans 3.53 Gb across 14 chromosomes, with an N50 length of 248.74 Mb. Genome annotation revealed that repetitive sequences constitute 80.82% of the genome size, and 83,269 protein-coding genes were predicted. Additionally, 4,360,538 bp of non-coding RNA were annotated. This genomic resource provides a foundation for further investigation into camptothecin biosynthesis pathways and plant phylogeny in N. nimmoniana.https://doi.org/10.1038/s41597-025-05484-w
spellingShingle Jiahui Wang
Xiaojie Ma
Xingyu Yang
Danni Yang
Tianping Huang
Yunqiang Yang
Yongping Yang
Chromosome-level genome assembly of Nothapodytes nimmoniana
Scientific Data
title Chromosome-level genome assembly of Nothapodytes nimmoniana
title_full Chromosome-level genome assembly of Nothapodytes nimmoniana
title_fullStr Chromosome-level genome assembly of Nothapodytes nimmoniana
title_full_unstemmed Chromosome-level genome assembly of Nothapodytes nimmoniana
title_short Chromosome-level genome assembly of Nothapodytes nimmoniana
title_sort chromosome level genome assembly of nothapodytes nimmoniana
url https://doi.org/10.1038/s41597-025-05484-w
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