A high-accuracy, low-cost blood test for Alzheimer’s disease: validating P-tau181/Aβ42 in real-world cohorts

A high-accuracy, low-cost blood test for Alzheimer’s disease: validating P-tau181/Aβ42 in real-world cohorts

ObjectiveTo evaluate the diagnostic performance of plasma P-tau181/Aβ42 measured via flow cytometry as a cost-effective tool for Alzheimer’s disease (AD) diagnosis.MethodsA cohort study involved 123 healthy controls, 60 AD/mild cognitive impairment (MCI) patients, 34 subcortical ischemic vascular di...

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Bibliographic Details
Main Authors: Dequan Liu, Hang Li, Qing Liu, Haiyan Li, Yuanyuan Tang, Kaiting Cheng, Tong Li, Yulan Chu, Xiaodong Jia, Wenying Yu, Hailan Zhou, Keqiang Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
plasma biomarkers
P-tau181/Aβ42
SIMOA
flow cytometry
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1599761/full
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