Correlation and distinction between stochastic gene transcription models with and without polymerase dynamics

Correlation and distinction between stochastic gene transcription models with and without polymerase dynamics

Polymerase dynamics (PD) is an important model for explaining transcriptional regulation in gene perturbation data. In this study, we conducted a detailed analysis of the dynamic behavior of stochastic gene transcription models with PD. We first derived an exact time-dependent formula of mRNA distri...

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Bibliographic Details
Main Authors: Chunjuan Zhu, Liang Chen, Zhishan Qiu, Jiaxin Chen, Feng Jiao, Jianshe Yu
Format: Article
Language:English
Published: American Physical Society 2025-04-01
Series:Physical Review Research
Online Access:http://doi.org/10.1103/PhysRevResearch.7.023050
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