Low-Level Laser Therapy and Calcitonin in Bone Repair: Densitometric Analysis
The aim of this work was to evaluate the association of low-level laser therapy (LLLT, 830 nm) and calcitonin in bone repair considering that bone healing remains a challenge to health professionals. Calcitonin has antiosteoclastic action and LLLT is a treatment that uses low-level lasers or light-e...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Photoenergy |
| Online Access: | http://dx.doi.org/10.1155/2012/829587 |
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| author | Tatiana Pinto Ribeiro Simone Bustamante Nascimento Claúdia Alessandra Cardoso Raduan Hage Janete Dias Almeida Emilia Angela Loschiavo Arisawa |
| author_facet | Tatiana Pinto Ribeiro Simone Bustamante Nascimento Claúdia Alessandra Cardoso Raduan Hage Janete Dias Almeida Emilia Angela Loschiavo Arisawa |
| author_sort | Tatiana Pinto Ribeiro |
| collection | DOAJ |
| description | The aim of this work was to evaluate the association of low-level laser therapy (LLLT, 830 nm) and calcitonin in bone repair considering that bone healing remains a challenge to health professionals. Calcitonin has antiosteoclastic action and LLLT is a treatment that uses low-level lasers or light-emitting diodes to alter cellular function. Both are used to improve bone healing. Densitometry is a clinical noninvasive valuable tool used to evaluate bone mineral density (BMD). Sixty male rats were submitted to bone defect with a trephine bur, randomly divided into four groups of 15 animals each: control (C); synthetic salmon calcitonin (Ca); LLLT (La); LLLT combined with calcitonin (LaCa). Animals from Ca and LaCa received 2 UI/Kg synthetic salmon calcitonin intramuscularly on alternate days after surgery. Animals from groups La and LaCa were treated with infrared LLLT (830 nm, 10 mW, 20 J/cm2, 6 s, contact mode). Five animals from each group were euthanized 7, 14, and 21 days after surgery and bone defects were analyzed by densitometry. Statistical analysis showed a significant difference in BMD values in LaCa group at 7 and 21 days (𝑃=0,005). The results of the densitometric study showed that LLLT (830 nm) combined with calcitonin improved bone repair. |
| format | Article |
| id | doaj-art-ed03f5543d934cb0ab027db7517ba18e |
| institution | Kabale University |
| issn | 1110-662X 1687-529X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Photoenergy |
| spelling | doaj-art-ed03f5543d934cb0ab027db7517ba18e2025-02-03T07:25:26ZengWileyInternational Journal of Photoenergy1110-662X1687-529X2012-01-01201210.1155/2012/829587829587Low-Level Laser Therapy and Calcitonin in Bone Repair: Densitometric AnalysisTatiana Pinto Ribeiro0Simone Bustamante Nascimento1Claúdia Alessandra Cardoso2Raduan Hage3Janete Dias Almeida4Emilia Angela Loschiavo Arisawa5Universidade do Vale do Paraíba (UNIVAP), 12244-000 São José dos Campos, SP, BrazilUniversidade do Vale do Paraíba (UNIVAP), 12244-000 São José dos Campos, SP, BrazilUniversidade do Vale do Paraíba (UNIVAP), 12244-000 São José dos Campos, SP, BrazilHealth Science Faculty, Universidade do Vale do Paraíba (UNIVAP), 12244-000 São José dos Campos, SP, BrazilDepartment of Biosciences and Oral Diagnosis, São José dos Campos Dental School, São Paulo State University (UNESP), 12245-000 São José dos Campos, SP, BrazilBiomedical Vibrational Spectroscopy Laboratory, Research and Development Institute (IP&D), Universidade do Vale do Paraíba (UNIVAP), 12244-000 São José dos Campos, SP, BrazilThe aim of this work was to evaluate the association of low-level laser therapy (LLLT, 830 nm) and calcitonin in bone repair considering that bone healing remains a challenge to health professionals. Calcitonin has antiosteoclastic action and LLLT is a treatment that uses low-level lasers or light-emitting diodes to alter cellular function. Both are used to improve bone healing. Densitometry is a clinical noninvasive valuable tool used to evaluate bone mineral density (BMD). Sixty male rats were submitted to bone defect with a trephine bur, randomly divided into four groups of 15 animals each: control (C); synthetic salmon calcitonin (Ca); LLLT (La); LLLT combined with calcitonin (LaCa). Animals from Ca and LaCa received 2 UI/Kg synthetic salmon calcitonin intramuscularly on alternate days after surgery. Animals from groups La and LaCa were treated with infrared LLLT (830 nm, 10 mW, 20 J/cm2, 6 s, contact mode). Five animals from each group were euthanized 7, 14, and 21 days after surgery and bone defects were analyzed by densitometry. Statistical analysis showed a significant difference in BMD values in LaCa group at 7 and 21 days (𝑃=0,005). The results of the densitometric study showed that LLLT (830 nm) combined with calcitonin improved bone repair.http://dx.doi.org/10.1155/2012/829587 |
| spellingShingle | Tatiana Pinto Ribeiro Simone Bustamante Nascimento Claúdia Alessandra Cardoso Raduan Hage Janete Dias Almeida Emilia Angela Loschiavo Arisawa Low-Level Laser Therapy and Calcitonin in Bone Repair: Densitometric Analysis International Journal of Photoenergy |
| title | Low-Level Laser Therapy and Calcitonin in Bone Repair: Densitometric Analysis |
| title_full | Low-Level Laser Therapy and Calcitonin in Bone Repair: Densitometric Analysis |
| title_fullStr | Low-Level Laser Therapy and Calcitonin in Bone Repair: Densitometric Analysis |
| title_full_unstemmed | Low-Level Laser Therapy and Calcitonin in Bone Repair: Densitometric Analysis |
| title_short | Low-Level Laser Therapy and Calcitonin in Bone Repair: Densitometric Analysis |
| title_sort | low level laser therapy and calcitonin in bone repair densitometric analysis |
| url | http://dx.doi.org/10.1155/2012/829587 |
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