The proportion of endometrial tumours associated with Lynch syndrome (PETALS): A prospective cross-sectional study.

The proportion of endometrial tumours associated with Lynch syndrome (PETALS): A prospective cross-sectional study.

<h4>Background</h4>Lynch syndrome (LS) predisposes to endometrial cancer (EC), colorectal cancer, and other cancers through inherited pathogenic variants affecting mismatch-repair (MMR) genes. Diagnosing LS in women with EC can reduce subsequent cancer mortality through colonoscopic surv...

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Main Authors: Neil A J Ryan, Raymond McMahon, Simon Tobi, Tristan Snowsill, Shona Esquibel, Andrew J Wallace, Sancha Bunstone, Naomi Bowers, Ioana E Mosneag, Sarah J Kitson, Helena O'Flynn, Neal C Ramchander, Vanitha N Sivalingam, Ian M Frayling, James Bolton, Rhona J McVey, D Gareth Evans, Emma J Crosbie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1003263&type=printable
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