Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective Study
This study aimed to identify the microbial etiology of infectious endophthalmitis and to determine the antibacterial susceptibilities of bacterial isolates at an eye hospital in South China. A retrospective analysis was carried out on 330 patients with clinically diagnosed infectious endophthalmitis...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2016/6764192 |
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| author | Fang Duan Kaili Wu Jingyu Liao Yongxin Zheng Zhaohui Yuan Junlian Tan Xiaofeng Lin |
| author_facet | Fang Duan Kaili Wu Jingyu Liao Yongxin Zheng Zhaohui Yuan Junlian Tan Xiaofeng Lin |
| author_sort | Fang Duan |
| collection | DOAJ |
| description | This study aimed to identify the microbial etiology of infectious endophthalmitis and to determine the antibacterial susceptibilities of bacterial isolates at an eye hospital in South China. A retrospective analysis was carried out on 330 patients with clinically diagnosed infectious endophthalmitis who underwent microbiological evaluation from January 2010 to December 2014. Of the 330 patients, 193 patients (58.5%) had posttraumatic endophthalmitis, 67 patients (20.3%) had postoperative endophthalmitis, 61 patients (18.5%) had endogenous endophthalmitis, and 9 patients (2.7%) had postcorneal infective endophthalmitis. Of the 105 cases (31.8%) of culture-positive endophthalmitis, 79 cases (75.2%) had bacterial growth and 26 cases (24.8%) had fungal growth. In posttraumatic endophthalmitis, Gram-positive bacteria were the predominant species, followed by Gram-negative bacteria and fungi. In endogenous endophthalmitis, Gram-negative bacteria were the predominant species, followed by fungi and Gram-positive bacteria. In postsurgical endophthalmitis, all infections were bacterial. However, in postcorneal infective endophthalmitis, all infections were fungal. Overall, levofloxacin showed the highest activity against bacterial isolates. There was a significant difference in the susceptibility to tobramycin between the isolates from posttraumatic and postoperative endophthalmitis (p<0.05). The results of this study identify the microbial spectrum of infectious endophthalmitis in this clinical setting. |
| format | Article |
| id | doaj-art-ece916657b6542a39c2c0db470aaf785 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-ece916657b6542a39c2c0db470aaf7852025-02-03T05:59:42ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/67641926764192Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective StudyFang Duan0Kaili Wu1Jingyu Liao2Yongxin Zheng3Zhaohui Yuan4Junlian Tan5Xiaofeng Lin6Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, 54 Xianlie Road, Guangzhou, Guangdong 510060, ChinaZhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, 54 Xianlie Road, Guangzhou, Guangdong 510060, ChinaZhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, 54 Xianlie Road, Guangzhou, Guangdong 510060, ChinaZhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, 54 Xianlie Road, Guangzhou, Guangdong 510060, ChinaZhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, 54 Xianlie Road, Guangzhou, Guangdong 510060, ChinaZhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, 54 Xianlie Road, Guangzhou, Guangdong 510060, ChinaZhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, 54 Xianlie Road, Guangzhou, Guangdong 510060, ChinaThis study aimed to identify the microbial etiology of infectious endophthalmitis and to determine the antibacterial susceptibilities of bacterial isolates at an eye hospital in South China. A retrospective analysis was carried out on 330 patients with clinically diagnosed infectious endophthalmitis who underwent microbiological evaluation from January 2010 to December 2014. Of the 330 patients, 193 patients (58.5%) had posttraumatic endophthalmitis, 67 patients (20.3%) had postoperative endophthalmitis, 61 patients (18.5%) had endogenous endophthalmitis, and 9 patients (2.7%) had postcorneal infective endophthalmitis. Of the 105 cases (31.8%) of culture-positive endophthalmitis, 79 cases (75.2%) had bacterial growth and 26 cases (24.8%) had fungal growth. In posttraumatic endophthalmitis, Gram-positive bacteria were the predominant species, followed by Gram-negative bacteria and fungi. In endogenous endophthalmitis, Gram-negative bacteria were the predominant species, followed by fungi and Gram-positive bacteria. In postsurgical endophthalmitis, all infections were bacterial. However, in postcorneal infective endophthalmitis, all infections were fungal. Overall, levofloxacin showed the highest activity against bacterial isolates. There was a significant difference in the susceptibility to tobramycin between the isolates from posttraumatic and postoperative endophthalmitis (p<0.05). The results of this study identify the microbial spectrum of infectious endophthalmitis in this clinical setting.http://dx.doi.org/10.1155/2016/6764192 |
| spellingShingle | Fang Duan Kaili Wu Jingyu Liao Yongxin Zheng Zhaohui Yuan Junlian Tan Xiaofeng Lin Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective Study Journal of Ophthalmology |
| title | Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective Study |
| title_full | Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective Study |
| title_fullStr | Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective Study |
| title_full_unstemmed | Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective Study |
| title_short | Causative Microorganisms of Infectious Endophthalmitis: A 5-Year Retrospective Study |
| title_sort | causative microorganisms of infectious endophthalmitis a 5 year retrospective study |
| url | http://dx.doi.org/10.1155/2016/6764192 |
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