Enhancement of orthodontic anchorage and retention by the local injection of strontium: An experimental study in rats

Objectives: To examine the clinical and histological effects of locally injected strontium on the anchoring unit of a rat model of an experimental relapsed tooth movement. Materials and methods: Thirty-six 10-week-old male Wister rats were randomly divided into two groups of 18 animals that were the...

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Main Authors: Munad J. Al-Duliamy, Nidhal H. Ghaib, Omar A. Kader, Bashar H. Abdullah
Format: Article
Language:English
Published: Springer 2015-01-01
Series:Saudi Dental Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1013905214000753
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author Munad J. Al-Duliamy
Nidhal H. Ghaib
Omar A. Kader
Bashar H. Abdullah
author_facet Munad J. Al-Duliamy
Nidhal H. Ghaib
Omar A. Kader
Bashar H. Abdullah
author_sort Munad J. Al-Duliamy
collection DOAJ
description Objectives: To examine the clinical and histological effects of locally injected strontium on the anchoring unit of a rat model of an experimental relapsed tooth movement. Materials and methods: Thirty-six 10-week-old male Wister rats were randomly divided into two groups of 18 animals that were then randomly divided into three subgroups of six animals corresponding to three observation periods: T1 = 1 week, T2 = 2 weeks, and T3 = 3 weeks. In the first experiment, both the right and left maxillary first molars were moved buccally with a standardized expansive spring. Strontium chloride solution was injected every 2 days into the subperiosteal area buccal to the left maxillary first molar (the experimental side). The right-sided first molar was injected with distilled water as a control. In the second experiment, maxillary first molars were moved buccally with the spring. After 3 weeks, the spring was removed. Two days before the spring removal, strontium chloride was injected into the palatal side of left-sided maxillary first molar and distilled water was injected into the palatal side of the right-sided maxillary first molar as in experiment 1. Results: At the end of the experimental period, significant levels of inhibition were noted in terms of both tooth movement and relapse movement in strontium-injected sides. Histological examinations showed that strontium enhanced the number of osteoblasts and reduced the number of osteoclasts. Conclusion: The local injection of strontium can inhibit the degree of experimental and relapsed tooth movement in a rat model. Keywords: Orthodontic anchorage, Retention, Strontium
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spelling doaj-art-ecd8dc0b246043b4b2ad6d948b2743a62025-08-20T02:22:06ZengSpringerSaudi Dental Journal1013-90522015-01-01271222910.1016/j.sdentj.2014.08.001Enhancement of orthodontic anchorage and retention by the local injection of strontium: An experimental study in ratsMunad J. Al-Duliamy0Nidhal H. Ghaib1Omar A. Kader2Bashar H. Abdullah3College of Dentistry, AL_Iraqia University, Iraq; Corresponding author.Department of Orthodontics, College of Dentistry, University of Baghdad, IraqDepartment of Oral Diagnosis, College of Dentistry, University of Baghdad, IraqDepartment of Oral Diagnosis, College of Dentistry, University of Baghdad, IraqObjectives: To examine the clinical and histological effects of locally injected strontium on the anchoring unit of a rat model of an experimental relapsed tooth movement. Materials and methods: Thirty-six 10-week-old male Wister rats were randomly divided into two groups of 18 animals that were then randomly divided into three subgroups of six animals corresponding to three observation periods: T1 = 1 week, T2 = 2 weeks, and T3 = 3 weeks. In the first experiment, both the right and left maxillary first molars were moved buccally with a standardized expansive spring. Strontium chloride solution was injected every 2 days into the subperiosteal area buccal to the left maxillary first molar (the experimental side). The right-sided first molar was injected with distilled water as a control. In the second experiment, maxillary first molars were moved buccally with the spring. After 3 weeks, the spring was removed. Two days before the spring removal, strontium chloride was injected into the palatal side of left-sided maxillary first molar and distilled water was injected into the palatal side of the right-sided maxillary first molar as in experiment 1. Results: At the end of the experimental period, significant levels of inhibition were noted in terms of both tooth movement and relapse movement in strontium-injected sides. Histological examinations showed that strontium enhanced the number of osteoblasts and reduced the number of osteoclasts. Conclusion: The local injection of strontium can inhibit the degree of experimental and relapsed tooth movement in a rat model. Keywords: Orthodontic anchorage, Retention, Strontiumhttp://www.sciencedirect.com/science/article/pii/S1013905214000753
spellingShingle Munad J. Al-Duliamy
Nidhal H. Ghaib
Omar A. Kader
Bashar H. Abdullah
Enhancement of orthodontic anchorage and retention by the local injection of strontium: An experimental study in rats
Saudi Dental Journal
title Enhancement of orthodontic anchorage and retention by the local injection of strontium: An experimental study in rats
title_full Enhancement of orthodontic anchorage and retention by the local injection of strontium: An experimental study in rats
title_fullStr Enhancement of orthodontic anchorage and retention by the local injection of strontium: An experimental study in rats
title_full_unstemmed Enhancement of orthodontic anchorage and retention by the local injection of strontium: An experimental study in rats
title_short Enhancement of orthodontic anchorage and retention by the local injection of strontium: An experimental study in rats
title_sort enhancement of orthodontic anchorage and retention by the local injection of strontium an experimental study in rats
url http://www.sciencedirect.com/science/article/pii/S1013905214000753
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AT nidhalhghaib enhancementoforthodonticanchorageandretentionbythelocalinjectionofstrontiumanexperimentalstudyinrats
AT omarakader enhancementoforthodonticanchorageandretentionbythelocalinjectionofstrontiumanexperimentalstudyinrats
AT basharhabdullah enhancementoforthodonticanchorageandretentionbythelocalinjectionofstrontiumanexperimentalstudyinrats