MANAGEMENT OF SYNCHRONIC LARGE LIVER METASTASIS IN A NON-OCCLUSIVE COLON TUMOR

ABSTRACT In patients with synchronic liver colorectal metastasis, resection of the primary tumor and liver metastases is the only potentially curative strategy. In such cases, there is no consensus on whether resection of the primary tumor and metastases should be performed simultaneously or whether...

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Main Authors: Eduardo José Brommelstroet Ramos, Hugo Pinto Marques, Martin Palavecino, Timothy Pawlik, Rene Adam, Olivier Soubrane, Paulo Herman, Ricardo Lemos Cotta-Pereira
Format: Article
Language:English
Published: Colégio Brasileiro de Cirurgia Digestiva 2025-01-01
Series:ABCD: Arquivos Brasileiros de Cirurgia Digestiva
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202024000100405&lng=en&tlng=en
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author Eduardo José Brommelstroet Ramos
Hugo Pinto Marques
Martin Palavecino
Timothy Pawlik
Rene Adam
Olivier Soubrane
Paulo Herman
Ricardo Lemos Cotta-Pereira
author_facet Eduardo José Brommelstroet Ramos
Hugo Pinto Marques
Martin Palavecino
Timothy Pawlik
Rene Adam
Olivier Soubrane
Paulo Herman
Ricardo Lemos Cotta-Pereira
author_sort Eduardo José Brommelstroet Ramos
collection DOAJ
description ABSTRACT In patients with synchronic liver colorectal metastasis, resection of the primary tumor and liver metastases is the only potentially curative strategy. In such cases, there is no consensus on whether resection of the primary tumor and metastases should be performed simultaneously or whether a staged approach should be performed (resection of the primary tumor and after, hepatectomy, or hepatectomy first). Patients with no bowel occlusion and with extensive liver disease are advised neoadjuvant oncological therapy. Similarly, various strategies such as portal vein embolization, liver deprivation, two-staged hepatectomy, and associating liver partition and portal vein ligation are available for patients who do not have a sufficient future liver remnant (generally 30-40% of the total). Therefore, a multidisciplinary approach is required for the treatment of these patients.
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id doaj-art-ecbcd1d1fdd94e76b1b0a61d73fc8208
institution Kabale University
issn 0102-6720
language English
publishDate 2025-01-01
publisher Colégio Brasileiro de Cirurgia Digestiva
record_format Article
series ABCD: Arquivos Brasileiros de Cirurgia Digestiva
spelling doaj-art-ecbcd1d1fdd94e76b1b0a61d73fc82082025-01-21T07:43:44ZengColégio Brasileiro de Cirurgia DigestivaABCD: Arquivos Brasileiros de Cirurgia Digestiva0102-67202025-01-013710.1590/0102-6720202400064e1858MANAGEMENT OF SYNCHRONIC LARGE LIVER METASTASIS IN A NON-OCCLUSIVE COLON TUMOREduardo José Brommelstroet Ramoshttps://orcid.org/0000-0002-7151-9956Hugo Pinto Marqueshttps://orcid.org/0000-0003-3540-0488Martin Palavecinohttps://orcid.org/0000-0002-5152-0159Timothy Pawlikhttps://orcid.org/0000-0002-7994-9870Rene Adamhttps://orcid.org/0000-0003-2169-5449Olivier Soubranehttps://orcid.org/0000-0002-2059-1237Paulo Hermanhttps://orcid.org/0000-0003-2859-5846Ricardo Lemos Cotta-Pereirahttps://orcid.org/0009-0006-0755-0883ABSTRACT In patients with synchronic liver colorectal metastasis, resection of the primary tumor and liver metastases is the only potentially curative strategy. In such cases, there is no consensus on whether resection of the primary tumor and metastases should be performed simultaneously or whether a staged approach should be performed (resection of the primary tumor and after, hepatectomy, or hepatectomy first). Patients with no bowel occlusion and with extensive liver disease are advised neoadjuvant oncological therapy. Similarly, various strategies such as portal vein embolization, liver deprivation, two-staged hepatectomy, and associating liver partition and portal vein ligation are available for patients who do not have a sufficient future liver remnant (generally 30-40% of the total). Therefore, a multidisciplinary approach is required for the treatment of these patients.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202024000100405&lng=en&tlng=enNeoplasm metastasisLiverColorectal neoplasmsChemotherapyHepatectomy
spellingShingle Eduardo José Brommelstroet Ramos
Hugo Pinto Marques
Martin Palavecino
Timothy Pawlik
Rene Adam
Olivier Soubrane
Paulo Herman
Ricardo Lemos Cotta-Pereira
MANAGEMENT OF SYNCHRONIC LARGE LIVER METASTASIS IN A NON-OCCLUSIVE COLON TUMOR
ABCD: Arquivos Brasileiros de Cirurgia Digestiva
Neoplasm metastasis
Liver
Colorectal neoplasms
Chemotherapy
Hepatectomy
title MANAGEMENT OF SYNCHRONIC LARGE LIVER METASTASIS IN A NON-OCCLUSIVE COLON TUMOR
title_full MANAGEMENT OF SYNCHRONIC LARGE LIVER METASTASIS IN A NON-OCCLUSIVE COLON TUMOR
title_fullStr MANAGEMENT OF SYNCHRONIC LARGE LIVER METASTASIS IN A NON-OCCLUSIVE COLON TUMOR
title_full_unstemmed MANAGEMENT OF SYNCHRONIC LARGE LIVER METASTASIS IN A NON-OCCLUSIVE COLON TUMOR
title_short MANAGEMENT OF SYNCHRONIC LARGE LIVER METASTASIS IN A NON-OCCLUSIVE COLON TUMOR
title_sort management of synchronic large liver metastasis in a non occlusive colon tumor
topic Neoplasm metastasis
Liver
Colorectal neoplasms
Chemotherapy
Hepatectomy
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202024000100405&lng=en&tlng=en
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