Radio navigation and photodynamic methods for intraoperative visualization of the parathyroid glands (review of literature)

Intraoperative identification of healthy parathyroid and parathyroid adenomas facilitate a favorable outcome of surgical treatment of patients with parathyroid diseases and various hyperparathyroidism’s forms. In doing so, it is important to preserve the entire parathyroid tissue, since unintentiona...

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Main Authors: P. N. Romashchenko, N. A. Maistrenko, D. S. Krivolapov, D. O. Vshivtsev
Format: Article
Language:Russian
Published: Pavlov First Saint Petersburg State Medical University 2020-08-01
Series:Вестник хирургии имени И.И. Грекова
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Online Access:https://www.vestnik-grekova.ru/jour/article/view/1441
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author P. N. Romashchenko
N. A. Maistrenko
D. S. Krivolapov
D. O. Vshivtsev
author_facet P. N. Romashchenko
N. A. Maistrenko
D. S. Krivolapov
D. O. Vshivtsev
author_sort P. N. Romashchenko
collection DOAJ
description Intraoperative identification of healthy parathyroid and parathyroid adenomas facilitate a favorable outcome of surgical treatment of patients with parathyroid diseases and various hyperparathyroidism’s forms. In doing so, it is important to preserve the entire parathyroid tissue, since unintentional damaging, removal or devascularization leads to the most common development of complication – hypoparathyroidism, which occasionally becomes permanent. Although, in case of surgical treatment of patients with hyperparathyroidism, the removal of the whole pathologically altered tissue is needed in order to avoid the persistence and recurrence hyperparathyroidism, as confirmed by intraoperative and postoperative parathyroid hormone examination. Up to recent time, surgeons could had relied only on pre-surgical localization of hyperfunctioning parathyroid glands, thorough knowledge of front neck anatomy and personal experience, which wasn’t always reliable to recognize the parathyroids intraoperatively and differentiate the healthy parathyroid tissue from adenoma. To solve these problems, the auxiliary navigation and visualization methods, based on application of radiopharmaceutical and fluorescent agents, tropic to parathyroid tissue, are being actively implemented to endocrine surgery nowadays. The comparative characteristic of modern methods for intraoperative visualization of the parathyroid glands, based on the worldwide literature data, is represented in this article.
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series Вестник хирургии имени И.И. Грекова
spelling doaj-art-ecb7fbca2c31443ea8bfaba65fd073c32025-08-20T03:02:29ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252020-08-01179311311910.24884/0042-4625-2020-179-3-113-1191150Radio navigation and photodynamic methods for intraoperative visualization of the parathyroid glands (review of literature)P. N. Romashchenko0N. A. Maistrenko1D. S. Krivolapov2D. O. Vshivtsev3Military Medical AcademyMilitary Medical AcademyMilitary Medical AcademyMilitary Medical AcademyIntraoperative identification of healthy parathyroid and parathyroid adenomas facilitate a favorable outcome of surgical treatment of patients with parathyroid diseases and various hyperparathyroidism’s forms. In doing so, it is important to preserve the entire parathyroid tissue, since unintentional damaging, removal or devascularization leads to the most common development of complication – hypoparathyroidism, which occasionally becomes permanent. Although, in case of surgical treatment of patients with hyperparathyroidism, the removal of the whole pathologically altered tissue is needed in order to avoid the persistence and recurrence hyperparathyroidism, as confirmed by intraoperative and postoperative parathyroid hormone examination. Up to recent time, surgeons could had relied only on pre-surgical localization of hyperfunctioning parathyroid glands, thorough knowledge of front neck anatomy and personal experience, which wasn’t always reliable to recognize the parathyroids intraoperatively and differentiate the healthy parathyroid tissue from adenoma. To solve these problems, the auxiliary navigation and visualization methods, based on application of radiopharmaceutical and fluorescent agents, tropic to parathyroid tissue, are being actively implemented to endocrine surgery nowadays. The comparative characteristic of modern methods for intraoperative visualization of the parathyroid glands, based on the worldwide literature data, is represented in this article.https://www.vestnik-grekova.ru/jour/article/view/1441surgery of the parathyroid glandshyperparathyroidismintraoperative parathyroid monitoringparathyroid monitoringfluorescence diagnosis
spellingShingle P. N. Romashchenko
N. A. Maistrenko
D. S. Krivolapov
D. O. Vshivtsev
Radio navigation and photodynamic methods for intraoperative visualization of the parathyroid glands (review of literature)
Вестник хирургии имени И.И. Грекова
surgery of the parathyroid glands
hyperparathyroidism
intraoperative parathyroid monitoring
parathyroid monitoring
fluorescence diagnosis
title Radio navigation and photodynamic methods for intraoperative visualization of the parathyroid glands (review of literature)
title_full Radio navigation and photodynamic methods for intraoperative visualization of the parathyroid glands (review of literature)
title_fullStr Radio navigation and photodynamic methods for intraoperative visualization of the parathyroid glands (review of literature)
title_full_unstemmed Radio navigation and photodynamic methods for intraoperative visualization of the parathyroid glands (review of literature)
title_short Radio navigation and photodynamic methods for intraoperative visualization of the parathyroid glands (review of literature)
title_sort radio navigation and photodynamic methods for intraoperative visualization of the parathyroid glands review of literature
topic surgery of the parathyroid glands
hyperparathyroidism
intraoperative parathyroid monitoring
parathyroid monitoring
fluorescence diagnosis
url https://www.vestnik-grekova.ru/jour/article/view/1441
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AT dskrivolapov radionavigationandphotodynamicmethodsforintraoperativevisualizationoftheparathyroidglandsreviewofliterature
AT dovshivtsev radionavigationandphotodynamicmethodsforintraoperativevisualizationoftheparathyroidglandsreviewofliterature