Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn’s Disease

Here we present an eleven-year-old male patient who had been diagnosed with common variable immunodeficiency (CVID) three years ago due to recurrent sinopulmonary infections. Two years later he had been diagnosed with Crohn’s disease (CD) due to diarrhea episodes which were unresponsive to the treat...

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Main Authors: Betül Ünal, Cumhur İbrahim Başsorgun, Sinem Çil Gönülcü, Aslı Uçar, Fatih Çelik, Gülsüm Özlem Elpek
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2015/348204
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author Betül Ünal
Cumhur İbrahim Başsorgun
Sinem Çil Gönülcü
Aslı Uçar
Fatih Çelik
Gülsüm Özlem Elpek
author_facet Betül Ünal
Cumhur İbrahim Başsorgun
Sinem Çil Gönülcü
Aslı Uçar
Fatih Çelik
Gülsüm Özlem Elpek
author_sort Betül Ünal
collection DOAJ
description Here we present an eleven-year-old male patient who had been diagnosed with common variable immunodeficiency (CVID) three years ago due to recurrent sinopulmonary infections. Two years later he had been diagnosed with Crohn’s disease (CD) due to diarrhea episodes which were unresponsive to the treatment. Depending on the active gastrointestinal bleeding and perforation he underwent total colectomy. Despite immunoglobulin and antiviral therapies, general condition of patient deteriorated and he died in the postoperative seventh day. Laboratory analysis was seronegative. CMV inclusion containing cells were detected in postmortem biopsies taken from liver, lungs, and lymph nodes.
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institution Kabale University
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publisher Wiley
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spelling doaj-art-eca6984948e940309f59aec26ab89b3a2025-02-03T01:27:12ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/348204348204Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn’s DiseaseBetül Ünal0Cumhur İbrahim Başsorgun1Sinem Çil Gönülcü2Aslı Uçar3Fatih Çelik4Gülsüm Özlem Elpek5Department of Pathology, School of Medicine, Akdeniz University, TurkeyDepartment of Pathology, School of Medicine, Akdeniz University, TurkeyDepartment of Pathology, School of Medicine, Akdeniz University, TurkeyDepartment of Pathology, School of Medicine, Akdeniz University, TurkeyDepartment of Pathology, School of Medicine, Akdeniz University, TurkeyDepartment of Pathology, School of Medicine, Akdeniz University, TurkeyHere we present an eleven-year-old male patient who had been diagnosed with common variable immunodeficiency (CVID) three years ago due to recurrent sinopulmonary infections. Two years later he had been diagnosed with Crohn’s disease (CD) due to diarrhea episodes which were unresponsive to the treatment. Depending on the active gastrointestinal bleeding and perforation he underwent total colectomy. Despite immunoglobulin and antiviral therapies, general condition of patient deteriorated and he died in the postoperative seventh day. Laboratory analysis was seronegative. CMV inclusion containing cells were detected in postmortem biopsies taken from liver, lungs, and lymph nodes.http://dx.doi.org/10.1155/2015/348204
spellingShingle Betül Ünal
Cumhur İbrahim Başsorgun
Sinem Çil Gönülcü
Aslı Uçar
Fatih Çelik
Gülsüm Özlem Elpek
Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn’s Disease
Case Reports in Medicine
title Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn’s Disease
title_full Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn’s Disease
title_fullStr Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn’s Disease
title_full_unstemmed Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn’s Disease
title_short Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn’s Disease
title_sort cytomegalovirus colitis with common variable immunodeficiency and crohn s disease
url http://dx.doi.org/10.1155/2015/348204
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