Synthesis, Spectroscopic, and Biological Studies on New Zirconium(IV) Porphyrins with Axial Ligand
A series of parasubstituted tetraphenylporphyrin zirconium(IV) salicylate complexes (SA/5-SSAZr(IV)RTPP, R = p-H, p-CH3, p-NO2, p-Cl, SA = salicylate, and 5-SSA = 5-sulfosalicylate) have been synthesized, and the spectral properties of free base porphyrins, their corresponding metallated, and axiall...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Bioinorganic Chemistry and Applications |
| Online Access: | http://dx.doi.org/10.1155/2013/903616 |
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| author | Gauri D. Bajju Gita Devi Sapna Katoch Madhulika Bhagat Deepmala Ashu Sujata Kundan Sunil Kumar Anand |
| author_facet | Gauri D. Bajju Gita Devi Sapna Katoch Madhulika Bhagat Deepmala Ashu Sujata Kundan Sunil Kumar Anand |
| author_sort | Gauri D. Bajju |
| collection | DOAJ |
| description | A series of parasubstituted tetraphenylporphyrin zirconium(IV) salicylate complexes (SA/5-SSAZr(IV)RTPP, R = p-H, p-CH3, p-NO2, p-Cl, SA = salicylate, and 5-SSA = 5-sulfosalicylate) have been synthesized, and the spectral properties of free base porphyrins, their corresponding metallated, and axially ligated zirconium(IV) porphyrin compounds were compared with each other. A detailed analysis of ultraviolet-visible (UV-vis), proton nulcear magnetic resonance (1H NMR) spectroscopy, infrared (IR) spectroscopy, and elemental analysis suggested the transformation from free base porphyrins to zirconium(IV) porphyrins. The ability of the metal in this complex for extra coordination of solvent molecules was confirmed by ESI-MS spectra. Besides the fluorescence, cyclic voltammetry, and thermogravimetric studies, the complexes were also screened for antimicrobial and anticancer activities. Among all the complexes, 5-SSAZr(p-NO2TPP) shows high antibacterial activity. |
| format | Article |
| id | doaj-art-ec7ee3d0bfc64ccf82d82164d9b21e1e |
| institution | Kabale University |
| issn | 1565-3633 1687-479X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Bioinorganic Chemistry and Applications |
| spelling | doaj-art-ec7ee3d0bfc64ccf82d82164d9b21e1e2025-02-03T01:20:29ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2013-01-01201310.1155/2013/903616903616Synthesis, Spectroscopic, and Biological Studies on New Zirconium(IV) Porphyrins with Axial LigandGauri D. Bajju0Gita Devi1Sapna Katoch2Madhulika Bhagat3Deepmala4Ashu5Sujata Kundan6Sunil Kumar Anand7P.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, IndiaP.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, IndiaP.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, IndiaSchool of Biotechnology, University of Jammu, Jammu, Jammu and Kashmir 180006, IndiaP.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, IndiaP.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, IndiaP.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, IndiaP.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, IndiaA series of parasubstituted tetraphenylporphyrin zirconium(IV) salicylate complexes (SA/5-SSAZr(IV)RTPP, R = p-H, p-CH3, p-NO2, p-Cl, SA = salicylate, and 5-SSA = 5-sulfosalicylate) have been synthesized, and the spectral properties of free base porphyrins, their corresponding metallated, and axially ligated zirconium(IV) porphyrin compounds were compared with each other. A detailed analysis of ultraviolet-visible (UV-vis), proton nulcear magnetic resonance (1H NMR) spectroscopy, infrared (IR) spectroscopy, and elemental analysis suggested the transformation from free base porphyrins to zirconium(IV) porphyrins. The ability of the metal in this complex for extra coordination of solvent molecules was confirmed by ESI-MS spectra. Besides the fluorescence, cyclic voltammetry, and thermogravimetric studies, the complexes were also screened for antimicrobial and anticancer activities. Among all the complexes, 5-SSAZr(p-NO2TPP) shows high antibacterial activity.http://dx.doi.org/10.1155/2013/903616 |
| spellingShingle | Gauri D. Bajju Gita Devi Sapna Katoch Madhulika Bhagat Deepmala Ashu Sujata Kundan Sunil Kumar Anand Synthesis, Spectroscopic, and Biological Studies on New Zirconium(IV) Porphyrins with Axial Ligand Bioinorganic Chemistry and Applications |
| title | Synthesis, Spectroscopic, and Biological Studies on New Zirconium(IV) Porphyrins with Axial Ligand |
| title_full | Synthesis, Spectroscopic, and Biological Studies on New Zirconium(IV) Porphyrins with Axial Ligand |
| title_fullStr | Synthesis, Spectroscopic, and Biological Studies on New Zirconium(IV) Porphyrins with Axial Ligand |
| title_full_unstemmed | Synthesis, Spectroscopic, and Biological Studies on New Zirconium(IV) Porphyrins with Axial Ligand |
| title_short | Synthesis, Spectroscopic, and Biological Studies on New Zirconium(IV) Porphyrins with Axial Ligand |
| title_sort | synthesis spectroscopic and biological studies on new zirconium iv porphyrins with axial ligand |
| url | http://dx.doi.org/10.1155/2013/903616 |
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