Urinary Markers of Tubular Injury in HIV-Infected Patients
Renal disease is a common complication of HIV-infected patients, associated with increased risk of cardiovascular events, progression to AIDS, AIDS-defining illness, and mortality. Early and accurate identification of renal disease is therefore crucial to improve patient outcomes. The use of serum c...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Biochemistry Research International |
| Online Access: | http://dx.doi.org/10.1155/2016/1501785 |
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| author | Temesgen Fiseha Angesom Gebreweld |
| author_facet | Temesgen Fiseha Angesom Gebreweld |
| author_sort | Temesgen Fiseha |
| collection | DOAJ |
| description | Renal disease is a common complication of HIV-infected patients, associated with increased risk of cardiovascular events, progression to AIDS, AIDS-defining illness, and mortality. Early and accurate identification of renal disease is therefore crucial to improve patient outcomes. The use of serum creatinine, along with proteinuria, to detect renal involvement is essentially to screen for markers of glomerular disease and may not be effective in detecting earlier stages of renal injury. Therefore, more sensitive and specific markers are needed in order to early identify HIV-infected patients at risk of renal disease. This review article summarizes some new and important urinary markers of tubular injury in HIV-infected patients and their clinical usefulness in the renal safety follow-up of TDF-treated patients. |
| format | Article |
| id | doaj-art-ec749979c3214873b0f0fce66d9f65fd |
| institution | Kabale University |
| issn | 2090-2247 2090-2255 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Biochemistry Research International |
| spelling | doaj-art-ec749979c3214873b0f0fce66d9f65fd2025-02-03T01:02:51ZengWileyBiochemistry Research International2090-22472090-22552016-01-01201610.1155/2016/15017851501785Urinary Markers of Tubular Injury in HIV-Infected PatientsTemesgen Fiseha0Angesom Gebreweld1Department of Clinical Laboratory Science, College of Medicine and Health Sciences, Wollo University, Dessie, EthiopiaDepartment of Clinical Laboratory Science, College of Medicine and Health Sciences, Wollo University, Dessie, EthiopiaRenal disease is a common complication of HIV-infected patients, associated with increased risk of cardiovascular events, progression to AIDS, AIDS-defining illness, and mortality. Early and accurate identification of renal disease is therefore crucial to improve patient outcomes. The use of serum creatinine, along with proteinuria, to detect renal involvement is essentially to screen for markers of glomerular disease and may not be effective in detecting earlier stages of renal injury. Therefore, more sensitive and specific markers are needed in order to early identify HIV-infected patients at risk of renal disease. This review article summarizes some new and important urinary markers of tubular injury in HIV-infected patients and their clinical usefulness in the renal safety follow-up of TDF-treated patients.http://dx.doi.org/10.1155/2016/1501785 |
| spellingShingle | Temesgen Fiseha Angesom Gebreweld Urinary Markers of Tubular Injury in HIV-Infected Patients Biochemistry Research International |
| title | Urinary Markers of Tubular Injury in HIV-Infected Patients |
| title_full | Urinary Markers of Tubular Injury in HIV-Infected Patients |
| title_fullStr | Urinary Markers of Tubular Injury in HIV-Infected Patients |
| title_full_unstemmed | Urinary Markers of Tubular Injury in HIV-Infected Patients |
| title_short | Urinary Markers of Tubular Injury in HIV-Infected Patients |
| title_sort | urinary markers of tubular injury in hiv infected patients |
| url | http://dx.doi.org/10.1155/2016/1501785 |
| work_keys_str_mv | AT temesgenfiseha urinarymarkersoftubularinjuryinhivinfectedpatients AT angesomgebreweld urinarymarkersoftubularinjuryinhivinfectedpatients |