RAGE and HMGB1 Expression in Orbital Tissue Microenvironment in Graves’ Ophthalmopathy

RAGE and HMGB1 Expression in Orbital Tissue Microenvironment in Graves’ Ophthalmopathy

Graves’ ophthalmopathy (GO) is a chronic autoimmune inflammatory disorder involving orbital tissues. A receptor for advanced glycation end products (RAGE) and its ligand high mobility group box 1 (HMGB1) protein trigger inflammation and cell proliferation and are involved in the pathogenesis of vari...

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Main Authors: Dominika Łacheta, Krzysztof B. Poślednik, Katarzyna Czerwaty, Nils Ludwig, Marta Molińska-Glura, Ireneusz Kantor, Anna Jabłońska-Pawlak, Piotr Miśkiewicz, Alicja Głuszko, Zygmunt Stopa, Jacek Brzost, Mirosław J. Szczepański
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2021/8891324
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