Integrated profiling of metaplastic breast cancer identifies putative master regulators of intratumoral heterogeneity

Integrated profiling of metaplastic breast cancer identifies putative master regulators of intratumoral heterogeneity

Abstract Metaplastic breast cancer (MpBC) is defined by the presence of various morphological elements, typically biphasic, with epithelial (e.g. no-special type (NST), squamous) and mesenchymal (e.g. spindle, chondroid, osteoid) components. The established clonality of the different components favo...

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Main Authors: Yufan Feng, Albert Xiong, Onkar Mulay, Anna Sokolova, Malcolm Lim, Benjamin Van Haeringen, Natasha McGuire, Xavier de Luca, Peter T. Simpson, Quan Nguyen, Sunil R. Lakhani, Amy E. McCart Reed
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-025-00807-x
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https://doi.org/10.1038/s41523-025-00807-x

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