Assessing inflammatory protein biomarkers in COPD subjects with and without alpha-1 antitrypsin deficiency
Abstract Rationale Individuals homozygous for the Alpha-1 Antitrypsin (AAT) Z allele (Pi*ZZ) exhibit heterogeneity in COPD risk. COPD occurrence in non-smokers with AAT deficiency (AATD) suggests that inflammatory processes may contribute to COPD risk independently of smoking. We hypothesized that i...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Respiratory Research |
| Online Access: | https://doi.org/10.1186/s12931-025-03320-8 |
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