Association between erectile dysfunction and the severity of obstruction to airflow in patients with chronic obstructive pulmonary disease

Objectives: The objective of this study was to explore a possible association between ED and the severity of airflow obstruction in patients with COPD. Materials and methods: A cross-sectional study was conducted using the International Index Erectile Function (IIEF), a scale validated and translate...

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Main Authors: María J. Pareja-Zabala, Carlos Aguirre, Abraham Alí-Munive, María C. Pareja-Zabala, Luis F. Guerrero, Sandra Huertas, Leidy P. Prada, Luis F. Giraldo-Cadavid
Format: Article
Language:English
Published: Sociedad Colombiana de Urología 2023-10-01
Series:Urología Colombiana
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Online Access:https://www.urologiacolombiana.com/frame_eng.php?id=29
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author María J. Pareja-Zabala
Carlos Aguirre
Abraham Alí-Munive
María C. Pareja-Zabala
Luis F. Guerrero
Sandra Huertas
Leidy P. Prada
Luis F. Giraldo-Cadavid
author_facet María J. Pareja-Zabala
Carlos Aguirre
Abraham Alí-Munive
María C. Pareja-Zabala
Luis F. Guerrero
Sandra Huertas
Leidy P. Prada
Luis F. Giraldo-Cadavid
author_sort María J. Pareja-Zabala
collection DOAJ
description Objectives: The objective of this study was to explore a possible association between ED and the severity of airflow obstruction in patients with COPD. Materials and methods: A cross-sectional study was conducted using the International Index Erectile Function (IIEF), a scale validated and translated to Spanish. Bivariate analyses between subgroups were made for quantitative variables using a t-test for means and Mann–Whitney U for medians; qualitative variables were compared using the χ2 test or Fisher’s test, depending on distribution. Confusion bias in the association between ED and airflow obstruction was controlled using a logistic regression model. Results: The Spanish version of the IIEF-15 scale was valid and applicable to the Colombian population. The prevalence of ED in COPD patients living at high altitudes was similar to that found at sea level. Such prevalence is higher than in general population. Beta-blockers increased 7 times the risk of ED, but we found no association between the degree of airflow obstruction and ED. Conclusion: Although the severity of COPD is not associated with ED, the prevalence of ED in COPD is higher than in general population. Therefore, ED screening in COPD patients using the IIEF could be justified. The strong association between beta-blockers and ED had not been previously described in patients with COPD but must be considered in their clinical management.
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spelling doaj-art-ec13ad6e50524845a2250dc9c17912a02025-02-02T06:40:12ZengSociedad Colombiana de UrologíaUrología Colombiana0120-789X2023-10-01324Association between erectile dysfunction and the severity of obstruction to airflow in patients with chronic obstructive pulmonary diseaseMaría J. Pareja-Zabala0Carlos Aguirre1Abraham Alí-Munive2María C. Pareja-Zabala3Luis F. Guerrero4Sandra Huertas5Leidy P. Prada6Luis F. Giraldo-Cadavid7Departamento de Investigación, Fundación Neumológica Colombiana, Bogotá; Departamento de Epidemiología, Universidad de la Sabana, Chía; ColombiaDirección de Educación, Fundación Neumológica Colombiana, Bogotá, ColombiaDirección Médica, Fundación Neumológica Colombiana, Bogotá, ColombiaFacultad de Medicina, Fundación Universitaria Sanitas, Bogotá, ColombiaConsulta Externa y Programas Especiales, Fundación Neumológica Colombiana, Bogotá, ColombiaConsulta Externa y Programas Especiales, Fundación Neumológica Colombiana, Bogotá, ColombiaConsulta Externa y Programas Especiales, Fundación Neumológica Colombiana, Bogotá, ColombiaServicio de Neumología Intervencionista, Fundación Neumológica Colombiana, Bogotá; Departamento de Epidemiología y Medicina Interna, Universidad de la Sabana, Chía. ColombiaObjectives: The objective of this study was to explore a possible association between ED and the severity of airflow obstruction in patients with COPD. Materials and methods: A cross-sectional study was conducted using the International Index Erectile Function (IIEF), a scale validated and translated to Spanish. Bivariate analyses between subgroups were made for quantitative variables using a t-test for means and Mann–Whitney U for medians; qualitative variables were compared using the χ2 test or Fisher’s test, depending on distribution. Confusion bias in the association between ED and airflow obstruction was controlled using a logistic regression model. Results: The Spanish version of the IIEF-15 scale was valid and applicable to the Colombian population. The prevalence of ED in COPD patients living at high altitudes was similar to that found at sea level. Such prevalence is higher than in general population. Beta-blockers increased 7 times the risk of ED, but we found no association between the degree of airflow obstruction and ED. Conclusion: Although the severity of COPD is not associated with ED, the prevalence of ED in COPD is higher than in general population. Therefore, ED screening in COPD patients using the IIEF could be justified. The strong association between beta-blockers and ED had not been previously described in patients with COPD but must be considered in their clinical management. https://www.urologiacolombiana.com/frame_eng.php?id=29Erectile dysfunction. COPD. International Index Erectile Function. Beta-blocker.
spellingShingle María J. Pareja-Zabala
Carlos Aguirre
Abraham Alí-Munive
María C. Pareja-Zabala
Luis F. Guerrero
Sandra Huertas
Leidy P. Prada
Luis F. Giraldo-Cadavid
Association between erectile dysfunction and the severity of obstruction to airflow in patients with chronic obstructive pulmonary disease
Urología Colombiana
Erectile dysfunction. COPD. International Index Erectile Function. Beta-blocker.
title Association between erectile dysfunction and the severity of obstruction to airflow in patients with chronic obstructive pulmonary disease
title_full Association between erectile dysfunction and the severity of obstruction to airflow in patients with chronic obstructive pulmonary disease
title_fullStr Association between erectile dysfunction and the severity of obstruction to airflow in patients with chronic obstructive pulmonary disease
title_full_unstemmed Association between erectile dysfunction and the severity of obstruction to airflow in patients with chronic obstructive pulmonary disease
title_short Association between erectile dysfunction and the severity of obstruction to airflow in patients with chronic obstructive pulmonary disease
title_sort association between erectile dysfunction and the severity of obstruction to airflow in patients with chronic obstructive pulmonary disease
topic Erectile dysfunction. COPD. International Index Erectile Function. Beta-blocker.
url https://www.urologiacolombiana.com/frame_eng.php?id=29
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