Immunomodulatory Effect of Phage Depolymerase Dep_kpv74 with Therapeutic Potential Against K2-Hypervirulent <i>Klebsiella pneumoniae</i>

Immunomodulatory Effect of Phage Depolymerase Dep_kpv74 with Therapeutic Potential Against K2-Hypervirulent <i>Klebsiella pneumoniae</i>

<b>Background:</b> The emergence of multidrug-resistant hypervirulent <i>Klebsiella pneumoniae</i> (hvKp) has made it difficult to treat and control infections caused by this bacterium. Previously, the therapeutic effectiveness of phage-encoded depolymerase Dep_kpv74 in a mou...

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Bibliographic Details
Main Authors: Nikolay V. Volozhantsev, Maria A. Makarova, Alena S. Kartseva, Marina V. Silkina, Valentina M. Krasilnikova, Egor A. Denisenko, Alexander I. Borzilov, Victoria V. Firstova
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antibiotics
Subjects:
<i>Klebsiella pneumoniae</i>
bacteriophage
polysaccharide depolymerase
lymphocyte proliferation
CD69
immunomodulation
Online Access:https://www.mdpi.com/2079-6382/14/1/44
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