CBD promotes antitumor activity by modulating tumor immune microenvironment in HPV associated head and neck squamous cell carcinoma

CBD promotes antitumor activity by modulating tumor immune microenvironment in HPV associated head and neck squamous cell carcinoma

IntroductionMarijuana use is associated with HPV-positive head and neck squamous cell carcinoma (HNSCC). However, cannabinoid use continues to increase in the US general population for recreational purposes as well as in cancer patients for palliative care. In this study, we explored the role of can...

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Bibliographic Details
Main Authors: Prakriti Sen, Sayed Sadat, Koji Ebisumoto, Riyam Al-Msari, Sayuri Miyauchi, Souvick Roy, Pardis Mohammadzadeh, Kristin Lips, Takuya Nakagawa, Robert Saddawi-Konefka, Andrew B. Sharabi, Joseph A. Califano
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
HPV-positive HNSCC
cannabinoid
MAPK
CD4+T cells
CD8+T cells
anti-tumor immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1528520/full
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