Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid Leukemia

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Main Authors: Georgios Pantouris, Leepakshi Khurana, Pathricia Tilstam, Alison Benner, Thomas Yoonsang Cho, Martin Lelaidier, Mathieu Perrée, Zoe Rosenbaum, Lin Leng, Francine Foss, Vineet Bhandari, Amit Verma, Richard Bucala, Elias J. Lolis
Format: Article
Language:English
Published: American Chemical Society 2025-04-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.4c10969
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author Georgios Pantouris
Leepakshi Khurana
Pathricia Tilstam
Alison Benner
Thomas Yoonsang Cho
Martin Lelaidier
Mathieu Perrée
Zoe Rosenbaum
Lin Leng
Francine Foss
Vineet Bhandari
Amit Verma
Richard Bucala
Elias J. Lolis
author_facet Georgios Pantouris
Leepakshi Khurana
Pathricia Tilstam
Alison Benner
Thomas Yoonsang Cho
Martin Lelaidier
Mathieu Perrée
Zoe Rosenbaum
Lin Leng
Francine Foss
Vineet Bhandari
Amit Verma
Richard Bucala
Elias J. Lolis
author_sort Georgios Pantouris
collection DOAJ
format Article
id doaj-art-ebe8ccc545ee4d9fa1b71e483ee3acf3
institution OA Journals
issn 2470-1343
language English
publishDate 2025-04-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-ebe8ccc545ee4d9fa1b71e483ee3acf32025-08-20T02:14:38ZengAmerican Chemical SocietyACS Omega2470-13432025-04-011017174411745210.1021/acsomega.4c10969Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid LeukemiaGeorgios Pantouris0Leepakshi Khurana1Pathricia Tilstam2Alison Benner3Thomas Yoonsang Cho4Martin Lelaidier5Mathieu Perrée6Zoe Rosenbaum7Lin Leng8Francine Foss9Vineet Bhandari10Amit Verma11Richard Bucala12Elias J. Lolis13Department of Chemistry, University of the Pacific, Stockton, California, United StatesDepartment of Pharmacology, School of Medicine, Yale University, New Haven, Connecticut, United StatesDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United StatesDepartment of Pharmacology, School of Medicine, Yale University, New Haven, Connecticut, United StatesDepartment of Pharmacology, School of Medicine, Yale University, New Haven, Connecticut, United StatesDiatech Oncology, Montreal, Quebec, CanadaDiatech Oncology, Montreal, Quebec, CanadaDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United StatesDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United StatesHematology and Stem Cell Transplantation, Yale University School of Medicine, New Haven, Connecticut, United StatesDivision of Neonatology, Department of Pediatrics, The Children’s Regional Hospital at Cooper, Camden, New Jersey, United StatesMontefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, United StatesDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United StatesDepartment of Pharmacology, School of Medicine, Yale University, New Haven, Connecticut, United Stateshttps://doi.org/10.1021/acsomega.4c10969
spellingShingle Georgios Pantouris
Leepakshi Khurana
Pathricia Tilstam
Alison Benner
Thomas Yoonsang Cho
Martin Lelaidier
Mathieu Perrée
Zoe Rosenbaum
Lin Leng
Francine Foss
Vineet Bhandari
Amit Verma
Richard Bucala
Elias J. Lolis
Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid Leukemia
ACS Omega
title Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid Leukemia
title_full Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid Leukemia
title_fullStr Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid Leukemia
title_full_unstemmed Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid Leukemia
title_short Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid Leukemia
title_sort inhibition of mif with an allosteric inhibitor triggers cell cycle arrest in acute myeloid leukemia
url https://doi.org/10.1021/acsomega.4c10969
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