Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus
We present a case of a 36-year-old female from Ghana who presented with atypical chest pain and shortness of breath and was found to have bilateral transudative pleural effusion and trivial pericardial effusion. Further work-up revealed serological markers consistent with active lupus and negative H...
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Wiley
2014-01-01
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Series: | Case Reports in Medicine |
Online Access: | http://dx.doi.org/10.1155/2014/732192 |
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author | Hassan Tariq Arsalan Rafiq Giovanni Franchin |
author_facet | Hassan Tariq Arsalan Rafiq Giovanni Franchin |
author_sort | Hassan Tariq |
collection | DOAJ |
description | We present a case of a 36-year-old female from Ghana who presented with atypical chest pain and shortness of breath and was found to have bilateral transudative pleural effusion and trivial pericardial effusion. Further work-up revealed serological markers consistent with active lupus and negative HIV. She developed rapid deterioration of her renal function requiring dialysis. Her renal biopsy showed collapsing focal segmental glomerulosclerosis with diffuse mesangial proliferative glomerulonephritis, consistent with lupus nephritis class II along with tubular degenerative changes. She was started on high dose steroids and later on mycophenolate mofetil. Her renal function slowly recovered to baseline. |
format | Article |
id | doaj-art-ebd9a191e0b74ba790b657b23949b967 |
institution | Kabale University |
issn | 1687-9627 1687-9635 |
language | English |
publishDate | 2014-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Medicine |
spelling | doaj-art-ebd9a191e0b74ba790b657b23949b9672025-02-03T06:07:09ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/732192732192Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus ErythematosusHassan Tariq0Arsalan Rafiq1Giovanni Franchin2Bronx Lebanon Hospital Center, Department of Medicine, 1650 Selwyn Avenue, Suit 10C, Bronx, NY 10457, USABronx Lebanon Hospital Center, Department of Medicine, 1650 Selwyn Avenue, Suit 10C, Bronx, NY 10457, USABronx Lebanon Hospital Center, Department of Medicine, 1650 Selwyn Avenue, Suit 10C, Bronx, NY 10457, USAWe present a case of a 36-year-old female from Ghana who presented with atypical chest pain and shortness of breath and was found to have bilateral transudative pleural effusion and trivial pericardial effusion. Further work-up revealed serological markers consistent with active lupus and negative HIV. She developed rapid deterioration of her renal function requiring dialysis. Her renal biopsy showed collapsing focal segmental glomerulosclerosis with diffuse mesangial proliferative glomerulonephritis, consistent with lupus nephritis class II along with tubular degenerative changes. She was started on high dose steroids and later on mycophenolate mofetil. Her renal function slowly recovered to baseline.http://dx.doi.org/10.1155/2014/732192 |
spellingShingle | Hassan Tariq Arsalan Rafiq Giovanni Franchin Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus Case Reports in Medicine |
title | Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus |
title_full | Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus |
title_fullStr | Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus |
title_full_unstemmed | Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus |
title_short | Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus |
title_sort | collapsing focal segmental glomerulosclerosis in a patient with systemic lupus erythematosus |
url | http://dx.doi.org/10.1155/2014/732192 |
work_keys_str_mv | AT hassantariq collapsingfocalsegmentalglomerulosclerosisinapatientwithsystemiclupuserythematosus AT arsalanrafiq collapsingfocalsegmentalglomerulosclerosisinapatientwithsystemiclupuserythematosus AT giovannifranchin collapsingfocalsegmentalglomerulosclerosisinapatientwithsystemiclupuserythematosus |