Study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype В
Experimental infection of 7-day-old chicks with the isolate of avian metapneumovirus Subtype В induced mild signs of respiratory infection and swelled infraorbital sinuses in 5-15 days post infection. Lesions in tissues of trachea, nasal passages and primary lymphoid organs were reported. Using real...
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| Format: | Article |
| Language: | English |
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Da Vinci Media
2018-04-01
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| Series: | Ветеринария сегодня |
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| Online Access: | https://veterinary.arriah.ru/jour/article/view/269 |
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| author | M. A. Volkova P. S. Yaroslavtseva V. Yu. Sosi Pato Rova T. L. Eroshina I. A. Chvala |
| author_facet | M. A. Volkova P. S. Yaroslavtseva V. Yu. Sosi Pato Rova T. L. Eroshina I. A. Chvala |
| author_sort | M. A. Volkova |
| collection | DOAJ |
| description | Experimental infection of 7-day-old chicks with the isolate of avian metapneumovirus Subtype В induced mild signs of respiratory infection and swelled infraorbital sinuses in 5-15 days post infection. Lesions in tissues of trachea, nasal passages and primary lymphoid organs were reported. Using real-time RT-PCR avian metapneumovirus genome was detected in the upper part of the respiratory tract, infraorbital sinuses and Harderian gland within 2-12 days post infection. The immune response was characterized by formation of humoral and local antibodies in 7-21 days post infection. In 3 days post infection increased percentage of CD8a+ T-cell subpopulation was reported in blood and spleen of the infected chicks. |
| format | Article |
| id | doaj-art-ebc39f6c58124161ae2f2292dca54e14 |
| institution | Kabale University |
| issn | 2304-196X 2658-6959 |
| language | English |
| publishDate | 2018-04-01 |
| publisher | Da Vinci Media |
| record_format | Article |
| series | Ветеринария сегодня |
| spelling | doaj-art-ebc39f6c58124161ae2f2292dca54e142025-02-06T09:52:06ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592018-04-01042934269Study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype ВM. A. Volkova0P. S. Yaroslavtseva1V. Yu. Sosi Pato Rova2T. L. Eroshina3I. A. Chvala4FGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirExperimental infection of 7-day-old chicks with the isolate of avian metapneumovirus Subtype В induced mild signs of respiratory infection and swelled infraorbital sinuses in 5-15 days post infection. Lesions in tissues of trachea, nasal passages and primary lymphoid organs were reported. Using real-time RT-PCR avian metapneumovirus genome was detected in the upper part of the respiratory tract, infraorbital sinuses and Harderian gland within 2-12 days post infection. The immune response was characterized by formation of humoral and local antibodies in 7-21 days post infection. In 3 days post infection increased percentage of CD8a+ T-cell subpopulation was reported in blood and spleen of the infected chicks.https://veterinary.arriah.ru/jour/article/view/269метапневмовирус птицклеточный и гуморальный иммунитетпатогенезavian metapneumoviruscell-mediated and antibody-mediated immunitypathogenesis |
| spellingShingle | M. A. Volkova P. S. Yaroslavtseva V. Yu. Sosi Pato Rova T. L. Eroshina I. A. Chvala Study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype В Ветеринария сегодня метапневмовирус птиц клеточный и гуморальный иммунитет патогенез avian metapneumovirus cell-mediated and antibody-mediated immunity pathogenesis |
| title | Study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype В |
| title_full | Study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype В |
| title_fullStr | Study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype В |
| title_full_unstemmed | Study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype В |
| title_short | Study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype В |
| title_sort | study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype в |
| topic | метапневмовирус птиц клеточный и гуморальный иммунитет патогенез avian metapneumovirus cell-mediated and antibody-mediated immunity pathogenesis |
| url | https://veterinary.arriah.ru/jour/article/view/269 |
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