Atypical Presentation of Acquired Hypoganglionosis in a Patient Taking Clozapine
Acquired hypoganglionosis (HG) is a rare enteric gastrointestinal neuromuscular disorder previously associated with chronic inflammation that can lead to constipation, ileus, and even death. There is little known about the pathophysiology of acquired hypoganglionosis, and it is unclear if medication...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/1272567 |
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| author | Catherine Gisi Anamaria Munteanu Lawrence Ku Samuel French Michael Fleischman Viktor Eysselein |
| author_facet | Catherine Gisi Anamaria Munteanu Lawrence Ku Samuel French Michael Fleischman Viktor Eysselein |
| author_sort | Catherine Gisi |
| collection | DOAJ |
| description | Acquired hypoganglionosis (HG) is a rare enteric gastrointestinal neuromuscular disorder previously associated with chronic inflammation that can lead to constipation, ileus, and even death. There is little known about the pathophysiology of acquired hypoganglionosis, and it is unclear if medications are related to the development of the disease. Clozapine is an atypical antipsychotic used to treat refractory schizophrenia that is well known for its side effects including agranulocytosis and gastrointestinal dysmotility. This is an unusual case of acquired hypoganglionosis in a patient with anticholinergic toxicity on clozapine therapy. |
| format | Article |
| id | doaj-art-ebc1ceb3f91949a3a4d803dbb1569c25 |
| institution | DOAJ |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-ebc1ceb3f91949a3a4d803dbb1569c252025-08-20T03:21:18ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362020-01-01202010.1155/2020/12725671272567Atypical Presentation of Acquired Hypoganglionosis in a Patient Taking ClozapineCatherine Gisi0Anamaria Munteanu1Lawrence Ku2Samuel French3Michael Fleischman4Viktor Eysselein5Department of Internal Medicine, Harbor-UCLA Medical Center, Torrance, CA, USADepartment of Pathology, Harbor-UCLA Medical Center, Torrance, CA, USADepartment of Internal Medicine, Harbor-UCLA Medical Center, Torrance, CA, USADepartment of Pathology, Harbor-UCLA Medical Center, Torrance, CA, USADepartment of Internal Medicine, Division of Gastroenterology, Harbor-UCLA Medical Center, Torrance, CA, USADepartment of Internal Medicine, Division of Gastroenterology, Harbor-UCLA Medical Center, Torrance, CA, USAAcquired hypoganglionosis (HG) is a rare enteric gastrointestinal neuromuscular disorder previously associated with chronic inflammation that can lead to constipation, ileus, and even death. There is little known about the pathophysiology of acquired hypoganglionosis, and it is unclear if medications are related to the development of the disease. Clozapine is an atypical antipsychotic used to treat refractory schizophrenia that is well known for its side effects including agranulocytosis and gastrointestinal dysmotility. This is an unusual case of acquired hypoganglionosis in a patient with anticholinergic toxicity on clozapine therapy.http://dx.doi.org/10.1155/2020/1272567 |
| spellingShingle | Catherine Gisi Anamaria Munteanu Lawrence Ku Samuel French Michael Fleischman Viktor Eysselein Atypical Presentation of Acquired Hypoganglionosis in a Patient Taking Clozapine Case Reports in Gastrointestinal Medicine |
| title | Atypical Presentation of Acquired Hypoganglionosis in a Patient Taking Clozapine |
| title_full | Atypical Presentation of Acquired Hypoganglionosis in a Patient Taking Clozapine |
| title_fullStr | Atypical Presentation of Acquired Hypoganglionosis in a Patient Taking Clozapine |
| title_full_unstemmed | Atypical Presentation of Acquired Hypoganglionosis in a Patient Taking Clozapine |
| title_short | Atypical Presentation of Acquired Hypoganglionosis in a Patient Taking Clozapine |
| title_sort | atypical presentation of acquired hypoganglionosis in a patient taking clozapine |
| url | http://dx.doi.org/10.1155/2020/1272567 |
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