Design of a new class of broad-spectrum therapeutics targeted to drug-resistant bacteria

We hypothesise that antimicrobial resistance (AMR) cannot be overcome by simply ‘drugging’ single biological targets, therefore, our focus is developing broad-spectrum therapeutics. Herein we present the synthesis of two novel spacer-linked, anthraquinone-triphenylphosphonium (AQ-TPP) conjugates (4)...

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Bibliographic Details
Main Authors: Amrutha Surendran, Agnes Turnbull, Allen Flockhart, Fern Findlay-Greene, Martyna Nowosielska, Donald Morrison, David J. Mincher, Samantha Donnellan
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:All Life
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Online Access:http://dx.doi.org/10.1080/26895293.2024.2379309
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